Results 1 to 10 of about 78,832 (263)

Schistosoma “Eggs-Iting” the Host: Granuloma Formation and Egg Excretion

Frontiers in Immunology, 2018
Schistosomiasis is a major cause of morbidity in humans invoked by chronic infection with parasitic trematodes of the genus Schistosoma. Schistosomes have a complex life-cycle involving infections of an aquatic snail intermediate host and a definitive ...
Christian Schwartz, Padraic G. Fallon, Padraic G. Fallon, Padraic G. Fallon   +3 more
doaj   +2 more sources

Non-typhoidal Salmonella intestinal carriage in a Schistosoma mansoni endemic community in a rural area of the Democratic Republic of Congo.

PLoS Neglected Tropical Diseases, 2020
BACKGROUND:Clinical observations and animal studies have suggested that Salmonella intestinal carriage is promoted by concurrent Schistosoma infection.
Lisette Mbuyi-Kalonji, Barbara Barbé, Gaëlle Nkoji, Joule Madinga, Clémentine Roucher, Sylvie Linsuke, Marie Hermy, Anne-Sophie Heroes, Wesley Mattheus, Katja Polman, Pascal Lutumba, Marie-France Phoba, Octavie Lunguya, Jan Jacobs   +13 more
doaj   +2 more sources

Schistosoma mansoni.

Trends in Parasitology, 2020
Timothy J C Anderson, Egie E Enabulele
semanticscholar   +4 more sources

Schistosoma Infection and Schistosoma-Derived Products Modulate the Immune Responses Associated with Protection against Type 2 Diabetes

Frontiers in Immunology, 2018
Studies on parasite-induced immunoregulatory mechanisms could contribute to the development of new therapies for inflammatory diseases such as type 2 diabetes (T2D), which is a chronic inflammatory disease characterized by persistent elevated glucose ...
Chun-Lian Tang, Zhi-Ming Liu, Yan Ru Gao, Fei Xiong   +3 more
doaj   +2 more sources

Th2 CD4+ T Cells Are Necessary and Sufficient for Schistosoma‐Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Inflammation underlies many forms of pulmonary hypertension (PH), including that resulting from Schistosoma infection, a major cause of PH worldwide.
Rahul Kumar, Claudia Mickael, Biruk Kassa, Linda Sanders, Dan Koyanagi, Daniel Hernandez‐Saavedra, Scott Freeman, Daniel Morales‐Cano, Angel Cogolludo, Amy S. McKee, Andrew P. Fontenot, Ghazwan Butrous, Rubin M. Tuder, Brian B. Graham   +13 more
doaj   +2 more sources

Unveiling the anti-neoplastic potential of Schistosoma mansoni-derived antigen against breast cancer: a pre-clinical study. [PDF]

Eur J Med Res
Background Cancer is a global health concern, with millions of new cases and deaths annually. Recently, immunotherapy has strengthened cancer treatment by harnessing the body's immune system to fight cancer. The search for advanced cancer immunotherapies
Eissa MM, Allam SRA, Ismail CA, Ghazala RA, El Skhawy N, Zaki IIA, Ibrahim EIE.   +6 more
europepmc   +2 more sources

The Role of Type 2 Inflammation in Schistosoma-Induced Pulmonary Hypertension

Frontiers in Immunology, 2019
Approximately 5% of individuals chronically infected with Schistosoma mansoni develop pulmonary hypertension (PH). The disease is progressive and often fatal, and treatment options are palliative, not curative. Recent studies have unraveled major players
Claudia S. Mickael, Brian B. Graham
doaj   +2 more sources

Booming Omics in Schistosoma [PDF]

Trends in Parasitology, 2021
Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al. and Wang et al. deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite ...
Le Govic, Yohann, Gourbal, Benjamin, Boissier, Jérôme   +2 more
openaire   +5 more sources

Life stage-specific glycosylation of extracellular vesicles from Schistosoma mansoni schistosomula and adult worms drives differential interaction with C-type lectin receptors DC-SIGN and MGL

Frontiers in Molecular Biosciences, 2023
Schistosomes can survive in mammalian hosts for many years, and this is facilitated by released parasite products that modulate the host’s immune system.
Marije E. Kuipers, Marije E. Kuipers, D. Linh Nguyen, Angela van Diepen, Lynn Mes, Erik Bos, Roman I. Koning, Esther N. M. Nolte-’t Hoen, Hermelijn H. Smits, Cornelis H. Hokke   +9 more
doaj   +1 more source

Population Genetic Structure and Hybridization of Schistosoma haematobium in Nigeria

Pathogens, 2022
Background: Schistosomiasis is a major poverty-related disease caused by dioecious parasitic flatworms of the genus Schistosoma with a health impact on both humans and animals.
A. M. Onyekwere, O. Rey, J. Allienne, M. C. Nwanchor, M. Alo, C. Uwa, J. Boissier   +6 more
semanticscholar   +1 more source