Results 41 to 50 of about 123,784 (291)

Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

eLife, 2019
CRISPR/Cas9-based genome editing has yet to be reported in species of the Platyhelminthes. We tested this approach by targeting omega-1 (ω1) of Schistosoma mansoni as proof of principle.
W. Ittiprasert, V. Mann, Shannon E. Karinshak, Avril Coghlan, G. Rinaldi, Geetha Sankaranarayanan, Apisit Chaidee, Toshihiko Tanno, C. Kumkhaek, P. Prangtaworn, Margaret M. Mentink-Kane, Christina J Cochran, P. Driguez, N. Holroyd, A. Tracey, Rutchanee Rodpai, B. Everts, C. Hokke, K. Hoffmann, M. Berriman, P. Brindley   +20 more
semanticscholar   +1 more source

Development of a Molecular Snail Xenomonitoring Assay to Detect Schistosoma haematobium and Schistosoma bovis Infections in their Bulinus Snail Hosts

Molecules, 2020
Schistosomiasis, a neglected tropical disease of medical and veterinary importance, transmitted through specific freshwater snail intermediate hosts, is targeted for elimination in several endemic regions in sub-Saharan Africa. Multi-disciplinary methods
T. Pennance, J. Archer, E. Lugli, Penelope Rostron, Felix Llanwarne, S. Ali, A. K. Amour, K. Suleiman, Sarah Li, D. Rollinson, J. Cable, S. Knopp, F. Allan, S. Ame, B. Webster   +14 more
semanticscholar   +1 more source

Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni [PDF]

, 2000
A schistosome infection is initiated when the parasite penetrates the skin of a susceptible host. Relatively large quantities of protein are released by transforming cercariae compared to later larval stages.
Coulson, P.S., Harrop, R., Jennings, N., Moutford, A.P., Wilson, R.A.   +4 more
core   +1 more source

Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]

, 2001
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K., Agnew A., Amory Soisson L., Aranda-Michel J., Araújo M. I., Ashton P. D., Bergquist N. R., Butterworth A. E., Butterworth A. E., Caldas I. R., Capron A., Carneiro-Santos P., Caulada-Benedetti Z., Chan M. S., Coulson P. S., de Clercq D., de Jonge N., Deelder A. M., Doetze A., Dunne D. W., Eberl M., Eberl M., Eberl M., Gryseels B, Gryseels B., Grzych J. M., Harrop R., Harrop R., Hsü S. Y., Jankovic D., Kardorff R., Kasper G., Katz N., Kuntz R. E., Mahmoud O. M., Malaquias L. C. C., Mansour M. M., Marguerite M., Medhat A., Montenegro S. M. L., Moser D., Olsen A., Omer F. M., Omer-Ali P., Pearce E. J., Pemberton R. M., Polman K., Prince A. M., Renquist D. M., Rieckmann K. H., Rocha M. O., Sadun E. H., Sadun E. H., Sher A., Smythies L. E., Sundstedt A., Tanner M., Velupillai P., Viana I. R., Viana I. R., von Lichtenberg F., von Lichtenberg F., Williams M. E., Wilson R. A., Yole D. S., Yole D. S.   +65 more
core   +2 more sources

Freshwater snails of biomedical importance in the Niger River Valley: evidence of temporal and spatial patterns in abundance, distribution and infection with Schistosoma spp.

Parasites & Vectors, 2019
Sound knowledge of the abundance and distribution of intermediate host snails is key to understanding schistosomiasis transmission and to inform effective interventions in endemic areas.
M. Rabone, Joris H. Wiethase, F. Allan, A. Gouvras, T. Pennance, A. Hamidou, B. Webster, R. Labbo, A. Emery, A. Garba, D. Rollinson   +10 more
semanticscholar   +1 more source

Interactions of Schistosoma and HIV in Sub-Saharan Africa: A Systematic Review.

American Journal of Tropical Medicine and Hygiene, 2020
Schistosomiasis is an acute and chronic parasitic disease caused by blood flukes of the genus Schistosoma. More than 220 million people worldwide were estimated to have active schistosomiasis in 2017, 90% of whom live on the African continent, but only ...
Briana D Furch, J. Koethe, V. Kayamba, D. Heimburger, P. Kelly   +4 more
semanticscholar   +1 more source

Evaluation of Loop-Mediated Isothermal Amplification (LAMP) in Urine Samples for the Diagnosis of Imported Schistosomiasis

Tropical Medicine and Infectious Disease, 2023
Migratory flows and international travel are triggering an increase in imported cases of schistosomiasis in non-endemic countries. The present study aims to evaluate the effectiveness of the LAMP technique on patients’ urine samples for the diagnosis of ...
Joaquín Salas-Coronas, María Pilar Luzón-García, Beatriz Crego-Vicente, Manuel Jesús Soriano-Pérez, Begoña Febrer-Sendra, José Vázquez-Villegas, Juan García-Bernalt Diego, Isabel María Cabeza-Barrera, Nerea Castillo-Fernández, Antonio Muro, María Dolores Bargues, Pedro Fernández-Soto   +11 more
doaj   +1 more source

The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata. [PDF]

, 2019
BackgroundThe full scope of the genes expressed by schistosomes during intramolluscan development has yet to be characterized. Understanding the gene products deployed by larval schistosomes in their snail hosts will provide insights into their ...
Bu, Lijing, Buddenborg, Sarah K, Hanelt, Ben, Kamel, Bishoy, Loker, Eric S, Mkoji, Gerald M, Zhang, Si-Ming   +6 more
core   +2 more sources

Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni

Nature Communications, 2019
Over 250 million people suffer from schistosomiasis, a tropical disease caused by parasitic flatworms known as schistosomes. Humans become infected by free-swimming, water-borne larvae, which penetrate the skin. The earliest intra-mammalian stage, called
C. L. Diaz Soria, Jayhun Lee, T. Chong, Avril Coghlan, A. Tracey, Matthew D. Young, T. Andrews, Christopher Hall, B. Ng, Kate A. Rawlinson, S. Doyle, Steven N. Leonard, Zhigang Lu, H. Bennett, G. Rinaldi, P. Newmark, M. Berriman   +16 more
semanticscholar   +1 more source

Chemosterilization of Schistosoma mansoni [PDF]

Nature, 1968
THE range of chemical agents which can produce sterility in experimental male rodents is gradually increasing. (For recent surveys, see Jackson1,2.) The list includes nitroaromatic compounds, for example, nitrofuranes, nitrothiazoles and nitropyrroles, besides a variety of compounds of the alkylating category.
Harold Jackson, P. Davies, Marion Bock
openaire   +3 more sources