Results 41 to 50 of about 3,518 (203)

Vaccines against the zoonotic trematodes Schistosoma japonicum, Fasciola hepatica and Fasciola gigantica [PDF]

, 2006
Schistosoma japonicum, Fasciola hepatica and F. gigantica are digenetic trematodes and, therefore, possess similar life cycles. While schistosomiasis japonica has for a long time been recognised as a major disease of both humans and animals, infection ...
Dalton, JP, McManus, DP
core   +1 more source

Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection

Journal of Cellular and Molecular Medicine, Volume 24, Issue 4, Page 2566-2572, February 2020., 2020
Abstract Schistosomiasis affects at least 200 million people in tropical and subtropical areas. The major pathology of schistosomiasis is egg‐induced liver granuloma characterized by an eosinophil‐rich inflammatory infiltration around the eggs, which subsequently leads to hepatic fibrosis and circulatory impairment in host.
Xiaojun Chen, Zhipeng Xu, Chuan Wei, XiaoWei Yang, Lei Xu, Sha Zhou, Jifeng Zhu, Chuan Su   +7 more
wiley   +1 more source

Sedum sarmentosum Total Flavonoids Alleviate Schistosomiasis‐Induced Liver Fibrosis by Altering TGF‐β1 and Smad7 Expression

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objectives. Schistosomiasis is a parasitic disease that affects over 142 million people worldwide. The main causes of death of schistosomiasis include liver granuloma and secondary hepatic cirrhosis resulting from severe fibrosis. Despite intensive research, controlling liver fibrosis associated with schistosomiasis remains challenging.
Peng-chun Yang, Wei-zhe Bai, Jing Wang, Cai-hua Yan, Wei-feng Huang, Shi-zhu Jiang, Konrad Urech   +6 more
wiley   +1 more source

Long‐Term Traditional Chinese Medicine Combined with NA Antiviral Therapy on Cirrhosis Incidence in Chronic Hepatitis B Patients in the Real‐World Setting: A Retrospective Study

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Objective. To evaluate the impact of long‐term Traditional Chinese Medicine (TCM) syndrome differentiation combined with antiviral therapy with Nucleos (t) ide analogues (NAs) on the incidence of cirrhosis in patients with chronic hepatitis B. Methods.
Zhi-Jun Hou, Jing-Hao Zhang, Xin Zhang, Qi-Hua Ling, Chao Zheng, Xiao-Jun Zhu, Zhen-Hua Zhou, Man Li, Xiao-Ni Kong, Xue-Hua Sun, Yue-Qiu Gao, Jian-Jie Chen, Maria G. Miguel   +12 more
wiley   +1 more source

The genetic diversity and geographical separation study of Oncomelania hupensis populations in mainland China using microsatellite loci [PDF]

, 2016
© 2016 Guan et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in ...
Abe, EM, Guan, W, Li, S-Z, Rollinson, D, Webster, BL, Zhou, X-N   +5 more
core   +1 more source

Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata [PDF]

, 2020
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
Crickmore, Neil, Duval, David, Galinier, Richard, Gourbal, Benjamin, Lassalle, Damien, Pinaud, Silvain, Tetreau, Guillaume   +6 more
core   +3 more sources

Current Status of Schistosomiasis Control and Prospects for Elimination in the Dongting Lake Region of the People’s Republic of China

Frontiers in Immunology, 2020
Schistosomiasis japonica is an ancient parasitic disease that has severely impacted human health causing a substantial disease burden not only to the Chinese people but also residents of other countries such as the Philippines, Indonesia and, before the ...
Fei-Yue Li, Fei-Yue Li, Xun-Ya Hou, Hong-Zhuan Tan, Gail M. Williams, Darren J. Gray, Catherine A. Gordon, Johanna Kurscheid, Archie C. A. Clements, Archie C. A. Clements, Yue-Sheng Li, Yue-Sheng Li, Donald P. McManus   +12 more
doaj   +1 more source

Circulating miRNAs: Potential Novel Biomarkers for Hepatopathology Progression and Diagnosis of Schistosomiasis Japonica in Two Murine Models. [PDF]

PLoS Neglected Tropical Diseases, 2015
Schistosomiasis remains a major public health issue, with an estimated 230 million people infected worldwide. Novel tools for early diagnosis and surveillance of schistosomiasis are currently needed.
Pengfei Cai, Geoffrey N Gobert, Hong You, Mary Duke, Donald P McManus   +4 more
doaj   +1 more source

Elimination of Schistosoma japonica in Central Sulawesi, Indonesia Intermediate Snail Control and Utilization Medicinal Plants

Journal of Parasite Science
Schistosomiasis is a zoonotic health problem caused by infection with the schistosoma class parasite, which lives in human blood vessels and around the intestines and bladder.
Acivrida Mega Charisma, Anjelline Naftalia, Alfian Anwar Putra Ramadhan, Rasyida Salma Aulia, Ferdina Amalia Solikhah, Husnul Muasyaroh, Vina Lailatul Maslakha, Nurul Hikmah, Ken Dyah Ayu Belina, Hilda Adinda, Siska Wulandari   +10 more
doaj   +1 more source

New Uses for Old Drugs: The Tale of Artemisinin Derivatives in the Elimination of Schistosomiasis Japonica in China

Molecules, 2014
Artemisinin (qinghaosu), extracted from the Chinese herb Artemisia annua L. in 1972, and its three major derivatives—artemether, artesunate and dihydroartemisinin—were firstly identified as antimalarials and found active against all species of the ...
Yi-Xin Liu, Wei Wu, Yue-Jin Liang, Zu-Liang Jie, Hui Wang, Wei Wang, Yi-Xin Huang   +6 more
doaj   +1 more source