Serum non‐coding RNAs for diagnosis and stage of liver fibrosis
Journal of Clinical Laboratory Analysis, Volume 36, Issue 10, October 2022., 2022 MicroRNAs, lncRNAs, circRNAs and exosomes which were released from liver enter into circulating vessels. The blood which contain these molecules are drawed from patients. Then the blood specimen are tested for diagnose of early fibrosis or stage fibrosis in patients with liver diseases. Abstract Background All chronic liver diseases could lead to liver
Chao Liu +6 more
wiley +1 more source
Journal of Tropical Medicine, Volume 2022, Issue 1, 2022., 2022 Schistosomiasis remains a major global public health concern. Currently, the control of this neglected tropical disease still depends on chemotherapy to reduce the prevalence and intensity of the parasite infection. It has been widely accepted that praziquantel is highly effective against all species of Schistosoma, and this agent is virtually the only
Xuehua Niu +5 more
wiley +1 more source
Evaluation of a real-time PCR assay for diagnosis of schistosomiasis japonica in the domestic goat. [PDF]
Parasit Vectors, 2020 Background Schistosomiasis japonica is an infectious disease caused by Schistosoma japonicum that seriously endangers human health. Domestic animals have important roles in disease transmission and goats are considered a primary reservoir host and source
Guo Q +12 more
europepmc +2 more sources
Higher frequency of circulating Vδ1 γδT cells in patients with advanced schistosomiasis
Parasite Immunology, Volume 43, Issue 10-11, October/November 2021., 2021 Abstract Gamma‐delta (γδ) T cells are the bridge between natural and adaptive immunity. In the present study, peripheral blood was collected from 13 patients with advanced schistosomiasis (schistosomiasis group) and 13 uninfected people (control group) to investigate the γδ T cells and their subtypes in human schistosomiasis.
Li Zheng +8 more
wiley +1 more source
Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica. [PDF]
PLoS ONE, 2014 Schistosomiasis japonica is a serious tropical parasitic disease in humans, which causes inflammation and fibrosis of the liver. Hepatic stellate cells (HSCs) are known to play an important role in schistosome-induced fibrosis, but their role in ...
Xing He +4 more
doaj +1 more source
Case Report: Multiple Schistosomiasis Japonica Cerebral Granulomas without Gastrointestinal System Involvement: Report of Two Cases and Review of Literature. [PDF]
Am J Trop Med Hyg, 2020 Most schistosomiasis japonica cerebral granulomas reported in the literature have been single and located in the cerebellum, and multiple lesions located in the cerebral hemisphere are uncommon and often misdiagnosed as metastases or gliomas. We describe
Shen J, Yuan L, Sun Y, Jiang X, Shao X.
europepmc +2 more sources
Noninvasive diagnosis of liver fibrosis in schistosomiasis japonica: Opportunities and challenges
, 2023 Portal Hypertension &Cirrhosis, Volume 2, Issue 1, Page 43-45, March 2023.
Tao Wang +4 more
wiley +1 more source
PAMAM-Lys, a novel vaccine delivery vector, enhances the protective effects of the SjC23 DNA vaccine against Schistosoma japonicum infection. [PDF]
PLoS ONE, 2014 BACKGROUND: Schistosomiasis japonica remains a major public-health concern in China. Praziquantel-based chemotherapy effectively reduces both infections and intensity; however, it can not prevent re-infection.
Xiaoting Wang +10 more
doaj +1 more source
IgG persistence showed weak clinical aspects in chronic schistosomiasis patients
Scientific Reports, 2023 Schistosomiasis is a chronic parasitic disease, which affects the quality of daily life of patients and imposes a huge burden on society. Hepatic fibrosis in response to continuous insult of eggs to the liver is a significant cause of morbidity and ...
Shudong Xie +8 more
doaj +1 more source
Pathogens, 2022 Schistosomiasis japonica caused by the trematode flukes of Schistosoma japonicum was one of the most grievous infectious diseases in China in the mid-20th century, while its elimination has been placed on the agenda of the national strategic plan of ...
Chao Lv +5 more
doaj +1 more source