Results 41 to 50 of about 620,945 (334)

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao, Zhuoma Danzhen, Yao Li, Junyu Zhu, Lan Chu, Zhang Yang   +5 more
wiley   +1 more source

Association Between SIRT1, Cytokines, and Metabolic Syndrome in Schizophrenia Patients With Olanzapine or Clozapine Monotherapy

Frontiers in Psychiatry, 2020
Objective: Previous studies consistently showed the interaction between Sirtuin 1 (SIRT1) and immune inflammation is significantly related to metabolic abnormalities, but their role in the pathogenesis of metabolic syndrome caused by second-generation ...
Xinyu Fang, Xinyu Fang, Lingfang Yu, Dandan Wang, Yan Chen, Yewei Wang, Zenan Wu, Ruimei Liu, Juanjuan Ren, Wei Tang, Chen Zhang   +10 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The impact of schizophrenia and intelligence on the relationship between age and brain volume

Schizophrenia Research: Cognition, 2019
Age has been shown to have an impact on both grey (GM) and white matter (WM) volume, with a steeper slope of age-related decline in schizophrenia compared to healthy controls.
Maria H. Jensen, Nikolaj Bak, Egill Rostrup, Mette Ø. Nielsen, Christos Pantelis, Birte Y. Glenthøj, Bjørn H. Ebdrup, Birgitte Fagerlund   +7 more
doaj   +1 more source

Dual‐Selective Terahertz‐Nanodisc Metasurfaces for Exploring Neurotransmitter Dynamics beyond Spectral Limitations

Advanced Materials, EarlyView.
Observation and detection of neurotransmitter dynamics in aqueous system has been hurdle for analytical fields due to its weak and reversible nature. A terahertz‐nanodisc metasurface which implements comprehensive detection over conformational change and selective sensing is introduced. Utilizing the THz regime photonics and biomimetic environment with
Taeyeon Kim, Yeon Kyung Lee, Yeeun Roh, Jaehun Park, Yong‐Sang Ryu, Hyun Seok Song, Minah Seo   +6 more
wiley   +1 more source

Quetiapine for schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2000
Quetiapine is an atypical antipsychotic with, theoretically, a low propensity for movement disorder adverse effects. It is used for the treatment of schizophrenia and other psychoses.To determine the effects of quetiapine for schizophrenia in comparison to placebo, and other antipsychotics.Electronic searches of the Cochrane Schizophrenia Group's ...
Manit Srisurapanont, Benchalak Maneeton, Narong Maneeton, Sudheer Lankappa, Rahul Gandhi   +4 more
openaire   +5 more sources

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

Frontiers in Psychiatry, 2018
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitoring ...
Tohru Ohnuma, Shohei Nishimon, Mayu Takeda, Takahiro Sannohe, Narimasa Katsuta, Heii Arai   +5 more
doaj   +1 more source

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

Advanced Science, EarlyView.
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu, Jia‐Wen Mo, Xunda Wang, Yinuo Ma, Shile Tian, Qi Wang, Peng‐Li Kong, Ziqi An, Li Ding, Jing Ren, Cheng‐Lin Lu, Chuanjun Tong, Ed X. Wu, Qiu‐gen Hu, Xiong Cao, Yanqiu Feng   +15 more
wiley   +1 more source

Epidural auditory event-related potentials in the rat to frequency and duration deviants: evidence of mismatch negativity?

Frontiers in Psychology, 2011
The capacity of the human brain to detect deviance in the acoustic environment pre-attentively is reflected in a brain event-related potential (ERP), mismatch negativity (MMN).
Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Patricia T Michie, Patricia T Michie, Patricia T Michie, Patricia T Michie, William R Fulham, William R Fulham, William R Fulham, William R Fulham, Juanita eTodd, Juanita eTodd, Juanita eTodd, Juanita eTodd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Michael eHunter, Michael eHunter, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson   +29 more
doaj   +1 more source