Results 71 to 80 of about 921,979 (317)

Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex. [PDF]

, 2008
Rhesus D incompatibility increases risk for schizophrenia, with some evidence that risk is limited to male offspring. The purpose of this study is to determine whether risk for schizophrenia due to Rhesus D incompatibility differs by offspring sex using ...
Hsieh, Hsin-Ju, Lonnqvist, Jouko, Mallery, Erin, Palmer, Christina GS, Peltonen, Leena, Sinsheimer, Janet S, Turunen, Joni A, Woodward, J Arthur   +7 more
core   +1 more source

Bayesian variable selection using an informed reversible jump in imaging genetics: an application to schizophrenia [PDF]

arXiv, 2023
From a practical perspective, proposals are one of the main bottleneck for any Markov Chain Monte Carlo (MCMC) algorithm. This paper suggests a novel data driven or informed proposal for reversible jump MCMC for Bayesian variable selection in the context of predictive risk assessment for schizophrenia based on imaging genetic data.
arxiv  

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

Proceedings of the National Academy of Sciences of the United States of America, 2001
Abnormalities of prefrontal cortical function are prominent features of schizophrenia and have been associated with genetic risk, suggesting that susceptibility genes for schizophrenia may impact on the molecular mechanisms of prefrontal function.
M. Egan, T. Goldberg, B. Kolachana, J. Callicott, C. Mazzanti, R. Straub, D. Goldman, D. Weinberger   +7 more
semanticscholar   +1 more source

Striatal Volume Increase After Six Weeks of Selective Dopamine D2/3 Receptor Blockade in First-Episode, Antipsychotic-Naïve Schizophrenia Patients

Frontiers in Neuroscience, 2020
Patients with chronic schizophrenia often display enlarged striatal volumes, and antipsychotic drugs may contribute via the dopamine D2/3 receptor (D2/3R) blockade.
Helle G. Andersen, Helle G. Andersen, Jayachandra M. Raghava, Jayachandra M. Raghava, Claus Svarer, Sanne Wulff, Louise B. Johansen, Patrick K. Antonsen, Patrick K. Antonsen, Mette Ø. Nielsen, Mette Ø. Nielsen, Egill Rostrup, Anthony C. Vernon, Anthony C. Vernon, Lars T. Jensen, Lars H. Pinborg, Birte Y. Glenthøj, Birte Y. Glenthøj, Bjørn H. Ebdrup, Bjørn H. Ebdrup   +19 more
doaj   +1 more source

Schizophrenia in older adults [PDF]

, 2011
Although the number of persons over the age of 55 with schizophrenia is expected to double over the next 20 years, the research data on older people with schizophrenia is limited.
American Psychiatric Association, Bleuler, Bleuler, Bridge, Collier, Collier, Collier, Elizabeth Collier, Jeanne M. Sorrell, Palmer, Roth, Snowden, World Health Organization   +12 more
core   +2 more sources

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

Frontiers in Psychiatry, 2018
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitoring ...
Tohru Ohnuma, Shohei Nishimon, Mayu Takeda, Takahiro Sannohe, Narimasa Katsuta, Heii Arai   +5 more
doaj   +1 more source

The dopamine hypothesis of schizophrenia: version III--the final common pathway.

Schizophrenia bulletin, 2009
The dopamine hypothesis of schizophrenia has been one of the most enduring ideas in psychiatry. Initially, the emphasis was on a role of hyperdopaminergia in the etiology of schizophrenia (version I), but it was subsequently reconceptualized to specify ...
O. Howes, S. Kapur
semanticscholar   +1 more source

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. [PDF]

, 2019
We generated cortical interneurons (cINs) from induced pluripotent stem cells derived from 14 healthy controls and 14 subjects with schizophrenia. Both healthy control cINs and schizophrenia cINs were authentic, fired spontaneously, received functional ...
Apud, Jose, Berman, Karen F, Bin Kim, Woong, Cho, Jun-Hyeong, Chung, Sangmi, Cohen, Bruce M, Cote, Sarah E, Coyle, Joseph T, Eggan, Kevin C, Eisenberg, Leonard M, Fukuda, Emi, Ghosh, Sulagna, Hirayama, Teruyoshi, Huang, Weihua, Kim, Hae-Young, Lanz, Thomas A, McPhie, Donna L, Moghadam, Alexander A, Nguyen, Christine, Ni, Peiyan, Noh, Haneul, Noyes, Elizabeth, Ongur, Dost, Park, James M, Park, Joshua J, Parsons, Teagan, Perlis, Roy H, Rapoport, Judith L, Shao, Zhicheng, Stanton, Patric K, Straub, Richard E, Weinberger, Daniel R, Xi, Hualin Simon, Yagi, Takeshi, Yin, Changhong, Zhao, Joyce, Zheng, Kelvin   +36 more
core   +1 more source

The thalamic reticular nucleus: a functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery [PDF]

, 2015
The thalamus (comprising many distinct nuclei) plays a key role in facilitating sensory discrimination and cognitive processes through connections with the cortex.
Morris, Brian J., Pratt, Judith A.
core   +1 more source

Epidural auditory event-related potentials in the rat to frequency and duration deviants: evidence of mismatch negativity?

Frontiers in Psychology, 2011
The capacity of the human brain to detect deviance in the acoustic environment pre-attentively is reflected in a brain event-related potential (ERP), mismatch negativity (MMN).
Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Patricia T Michie, Patricia T Michie, Patricia T Michie, Patricia T Michie, William R Fulham, William R Fulham, William R Fulham, William R Fulham, Juanita eTodd, Juanita eTodd, Juanita eTodd, Juanita eTodd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Michael eHunter, Michael eHunter, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson   +29 more
doaj   +1 more source