Results 71 to 80 of about 1,069,369 (339)

A Systematic Review of the Prevalence of Schizophrenia

PLoS Medicine, 2005
Background Understanding the prevalence of schizophrenia has important implications for both health service planning and risk factor epidemiology. The aims of this review are to systematically identify and collate studies describing the prevalence of ...
S. Saha, D. Chant, J. Welham, J. Mcgrath
semanticscholar   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

Frontiers in Psychiatry, 2018
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitoring ...
Tohru Ohnuma, Shohei Nishimon, Mayu Takeda, Takahiro Sannohe, Narimasa Katsuta, Heii Arai   +5 more
doaj   +1 more source

Differential expression of diacylglycerol kinase ζ is involved in inferior parietal lobule-related dysfunction in schizophrenia with cognitive impairments

BMC Psychiatry, 2023
Background Cognitive impairment is the main factor in the poor prognosis of schizophrenia, but its mechanism remains unclear. The inferior parietal lobule (IPL) is related to various clinical symptoms and cognitive impairment in schizophrenia.
Xiao-Fan Liu, Shu-Wan Zhao, Jin-Jin Cui, Yue-Wen Gu, Jing-Wen Fan, Yu-Fei Fu, Ya-Hong Zhang, Hong Yin, Kun Chen, Long-Biao Cui   +9 more
doaj   +1 more source

Evaluating Depressive Symptoms in Schizophrenia: A Psychometric Comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale [PDF]

, 2012
Background: The aim of this study was to compare two measures of depression in patients with schizophrenia and schizophrenia spectrum disorder, including patients with delusional and schizoaffective disorder, to conclude implications for their ...
Addington D, Addington D, Addington D, Bagby RM, Bernard D, Collins AA, Conley RR, Cording C, Craig TJ, Dieter Naber, Eckart Rüther, Fleck MP, Florian Seemüller, Gerd Laux, Goldman RS, Hamilton M, Hamilton M, Hans-Jürgen Möller, Herbert Pfeiffer, Humphreys LG, Isabella Heuser, Jager M, Jager M, Joachim Klosterkötter, Kay SR, Kim SW, Kontaxakis VP, Lancon C, Lutz G. Schmidt, Maggini C, Markus Gastpar, Markus Jäger, Matthias R. Lemke, Max Schmauss, Michael Obermeier, Michael Riedel, Moller H-J, Muller MJ, Müller MJ, Rebecca Schennach, Reine G, Resnick SG, Rocca P, Sands JR, Sarro S, Shafer AB, Stefan Klingberg, Tapp A, Tollefson GD, Wolfgang Gaebel, Wolfgang Maier, Wolwer W, Zisook S   +52 more
core   +1 more source

Nonsocial and social cognition in schizophrenia: current evidence and future directions

World Psychiatry, 2019
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social cognitive domains. It is a core feature of the illness, and one with substantial implications for treatment and prognosis.
Michael F. Green, W. Horan, Junghee Lee
semanticscholar   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

Connectivity-enhanced diffusion analysis reveals white matter density disruptions in first episode and chronic schizophrenia. [PDF]

, 2018
Reduced fractional anisotropy (FA) is a well-established correlate of schizophrenia, but it remains unclear whether these tensor-based differences are the result of axon damage and/or organizational changes and whether the changes are progressive in the ...
Bearden, Carrie E, Cannon, Tyrone D, Grazioplene, Rachael G, Haut, Kristen, Nuechterlein, Keith H, Subotnik, Kenneth L, Ventura, Joseph   +6 more
core   +3 more sources

Comparative genetic architectures of schizophrenia in East Asian and European populations

Nature Genetics, 2018
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk globally. Large-scale schizophrenia genetic studies have reported primarily on European ancestry samples, potentially missing important biological insights. Here, we
Max W. Y. Lam, Chia-Yen Chen, Zhiqiang Li, Alicia R. Martin, J. Bryois, Xixian Ma, Héléna A. Gaspar, M. Ikeda, Beben Benyamin, Brielin C. Brown, Ruize Liu, Wei Zhou, L. Guan, Y. Kamatani, Sung-Wan Kim, M. Kubo, A. Kusumawardhani, Chih-Min Liu, Hong Ma, S. Periyasamy, A. Takahashi, Zhida Xu, Hao Yu, Feng Zhu, Wei J. Chen, Stephen Faraone, S. Glatt, Lin He, S. Hyman, H. Hwu, S. Mccarroll, B. Neale, P. Sklar, D. Wildenauer, Xin Yu, Dai Zhang, B. Mowry, Jimmy Lee, P. Holmans, Shuhua Xu, Patrick F. Sullivan, S. Ripke, M. O’Donovan, M. Daly, Shengying Qin, P. Sham, N. Iwata, K. Hong, S. Schwab, W. Yue, Ming Tsuang, J. Liu, Xiancang Ma, R. Kahn, Yongyong Shi, Hailiang Huang   +55 more
semanticscholar   +1 more source