Results 71 to 80 of about 620,945 (334)

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Current Concepts and Treatments of Schizophrenia

Molecules, 2018
Schizophrenia is a debilitating mental illness which involves three groups of symptoms, i.e., positive, negative and cognitive, and has major public health implications. According to various sources, it affects up to 1% of the population.
Piotr Stępnicki, Magda Kondej, A. Kaczor   +2 more
semanticscholar   +1 more source

Superconductivity in Hourglass Dirac Chain Metals (Ti, Hf)IrGe

Advanced Science, EarlyView.
We report the discovery of ternary germanide superconductors MIrGe (M = Ti, Hf) that host hourglass Dirac chains protected by nonsymmorphic symmetry. These compounds exhibit bulk type‐II superconductivity with fully gapped states and preserved time‐reversal symmetry, as confirmed by µSR measurements.
Pavan Kumar Meena, Dibyendu Samanta, Sonika Jangid, Roshan Kumar Kushwaha, Rhea Stewart, Adrian D. Hillier, Sudeep Kumar Ghosh, Ravi Prakash Singh   +7 more
wiley   +1 more source

Peripheral Lipid Signatures, Metabolic Dysfunction, and Pathophysiology in Schizophrenia Spectrum Disorders

Metabolites
Metabolic dysfunction is commonly observed in schizophrenia spectrum disorders (SSDs). The causes of metabolic comorbidity in SSDs are complex and include intrinsic or biological factors linked to the disorder, which are compounded by antipsychotic (AP ...
Sally Wu, Kristoffer J. Panganiban, Jiwon Lee, Dan Li, Emily C.C. Smith, Kateryna Maksyutynska, Bailey Humber, Tariq Ahmed, Sri Mahavir Agarwal, Kristen Ward, Margaret Hahn   +10 more
doaj   +1 more source

Unraveling Multimodal Brain Signatures: Deciphering Transdiagnostic Dimensions of Psychopathology in Adolescents

Advanced Intelligent Systems, EarlyView.
This study, utilizing two large‐cohort datasets, employs interpretable neural networks. It demonstrates that incorporating brain morphology and functional and structural networks enhances predictive accuracy for general psychopathology and its dimensions.
Jing Xia, Nanguang Chen, Anqi Qiu
wiley   +1 more source

No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial

Frontiers in Psychiatry, 2020
BackgroundIndividuals at ultra-high risk for psychosis (UHR) present with subtle alterations in cerebral white matter (WM), which appear to be associated with clinical and functional outcome.
Tina D. Kristensen, Tina D. Kristensen, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Carsten Hjorthøj, Carsten Hjorthøj, René C. W. Mandl, René C. W. Mandl, Jayachandra M. Raghava, Jayachandra M. Raghava, Jens Richardt M. Jepsen, Jens Richardt M. Jepsen, Birgitte Fagerlund, Birgitte Fagerlund, Louise B. Glenthøj, Louise B. Glenthøj, Christina Wenneberg, Christina Wenneberg, Kristine Krakauer, Christos Pantelis, Christos Pantelis, Birte Y. Glenthøj, Birte Y. Glenthøj, Merete Nordentoft, Merete Nordentoft, Merete Nordentoft   +26 more
doaj   +1 more source

Who puts the “support” in supportive housing? The relationship between housing staff support and resident experiences, and the potential moderating role of self‐determination

American Journal of Community Psychology, EarlyView.
Abstract The provision of residential and community‐based services for individuals with serious mental illness (SMI) has become increasingly important following the deinstitutionalization movement. Much of the existing research on supportive housing focuses on housing outcomes rather than exploring how the program helps its residents thrive in the ...
Kenna E. Dickard, Greg Townley
wiley   +1 more source

Attenuated mismatch negativity in patients with first-episode antipsychotic-naive schizophrenia using a source-resolved method

NeuroImage: Clinical, 2019
Background: Mismatch negativity (MMN) is a measure of pre-attentive auditory information processing related to change detection. Traditional scalp-level EEG methods consistently find attenuated MMN in patients with chronic but not first-episode ...
M. Randau, B. Oranje, M. Miyakoshi, S. Makeig, B. Fagerlund, B. Glenthøj, N. Bak   +6 more
doaj   +1 more source

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Nature, 2022
V. Trubetskoy, A. Pardiñas, Ting Qi, Georgia Panagiotaropoulou, S. Awasthi, T. Bigdeli, J. Bryois, Chia-Yen Chen, Charlotte A Dennison, L. Hall, Max W. Y. Lam, Kyoko Watanabe, O. Frei, T. Ge, J. Harwood, F. Koopmans, S. Magnússon, A. Richards, J. Sidorenko, Yang Wu, Jian Zeng, J. Grove, Minsoo Kim, Zhiqiang Li, G. Voloudakis, Wen Zhang, M. Adams, I. Agartz, Elizabeth G. Atkinson, E. Agerbo, M. A. Al Eissa, M. Albus, Madeline Alexander, B. Alizadeh, K. Alptekin, T. Als, F. Amin, V. Arolt, M. Arrojo, L. Athanasiu, M. Azevedo, S. Bacanu, N. Bass, M. Begemann, R. Belliveau, J. Bene, Beben Benyamin, Sarah E. Bergen, G. Blasi, J. Bobes, S. Bonassi, A. Braun, R. Bressan, E. Bromet, R. Bruggeman, P. Buckley, R. Buckner, J. Bybjerg-Grauholm, W. Cahn, M. Cairns, M. Calkins, V. Carr, D. Castle, S. Catts, K. Chambert, R. Chan, B. Chaumette, Wei Cheng, E. Cheung, S. Chong, D. Cohen, A. Consoli, Q. Cordeiro, J. Costas, C. Curtis, M. Davidson, K. Davis, L. de Haan, F. Degenhardt, L. DeLisi, D. Demontis, F. Dickerson, D. Dikeos, T. Dinan, S. Djurovic, J. Duan, G. Ducci, F. Dudbridge, J. Eriksson, L. Fañanás, S. Faraone, A. Fiorentino, A. Forstner, J. Frank, N. Freimer, M. Fromer, A. Frustaci, A. Gadelha, G. Genovese, E. Gershon, M. Giannitelli, I. Giegling, P. Giusti-Rodríguez, S. Godard, J. Goldstein, Javier González Peñas, A. González-Pinto, S. Gopal, J. Gratten, Michael F. Green, T. Greenwood, O. Guillin, Sinan Gülöksüz, R. Gur, R. Gur, B. Gutiérrez, E. Hahn, H. Hakonarson, V. Haroutunian, A. Hartmann, C. Harvey, C. Hayward, F. Henskens, S. Herms, P. Hoffmann, D. Howrigan, M. Ikeda, C. Iyegbe, I. Joa, A. Julià, A. Kähler, T. Kam-Thong, Y. Kamatani, Sena Karachanak-Yankova, O. Kebir, M. Keller, B. Kelly, A. Khrunin, Sung-Wan Kim, J. Kloviņš, N. Kondratiev, B. Konte, J. Kraft, M. Kubo, V. Kučinskas, Z. Kučinskienė, A. Kusumawardhani, Hana Kuzelova-Ptackova, S. Landi, L. Lazzeroni, Phil H. Lee, S. Legge, D. Lehrer, R. Lencer, B. Lerer, Miaoxin Li, J. Lieberman, G. Light, S. Limborska, Chih-Min Liu, J. Lönnqvist, C. Loughland, J. Lubiński, J. Luykx, A. Lynham, M. Macek, Andrew Mackinnon, P. Magnusson, B. Maher, W. Maier, D. Malaspina, J. Mallet, S. Marder, S. Marsal, Alicia R. Martin, L. Martorell, M. Mattheisen, R. McCarley, C. Mcdonald, J. Mcgrath, H. Medeiros, S. Meier, B. Melegh, I. Melle, R. Mesholam-Gately, A. Metspalu, P. Michie, L. Milani, V. Milanova, M. Mitjans, E. Molden, E. Molina, M. Moltó, V. Mondelli, C. Moreno, C. Morley, G. Muntané, K. Murphy, I. Myin‐Germeys, I. Nenadić, G. Nestadt, L. Nikitina-Zake, Cristiano Noto, K. Nuechterlein, N. O’Brien, F. O’Neill, Sang-Yun Oh, A. Olincy, V. Ota, C. Pantelis, G. Papadimitriou, M. Parellada, T. Paunio, R. Pellegrino, S. Periyasamy, D. Perkins, B. Pfuhlmann, O. Pietiläinen, J. Pimm, D. Porteous, J. Powell, D. Quattrone, D. Quested, A. Radant, A. Rampino, M. Rapaport, A. Rautanen, A. Reichenberg, Cheryl A. Roe, J. Roffman, Julian Roth, M. Rothermundt, B. Rutten, Safa Saker-Delye, V. Salomaa, J. Sanjuán, M. Santoro, A. Savitz, U. Schall, Rodney J. Scott, L. Seidman, S. Sharp, Jianxin Shi, L. Siever, E. Sigurdsson, K. Sim, Nora Skarabis, P. Slominsky, H. So, J. Sobell, E. Söderman, H. Stain, N. Steen, Agnes A. Steixner-Kumar, Elisabeth Stögmann, W. Stone, R. Straub, F. Streit, E. Strengman, T. Stroup, M. Subramaniam, Catherine A. Sugar, J. Suvisaari, D. Svrakic, N. Swerdlow, J. Szatkiewicz, T. Ta, A. Takahashi, C. Terao, F. Thibaut, D. Toncheva, P. Tooney, Silvia Torretta, S. Tosato, G. Tura, B. Turetsky, A. Üçok, A. Vaaler, T. van Amelsvoort, R. van Winkel, J. Veijola, J. Waddington, H. Walter, A. Waterreus, B. Webb, M. Weiser, N. Williams, S. Witt, B. Wormley, J. Wu, Zhida Xu, R. Yolken, C. Zai, Wei Zhou, Feng Zhu, F. Zimprich, E. Atbasoglu, M. Ayub, C. Benner, A. Bertolino, D. Black, N. Bray, G. Breen, N. Buccola, W. Byerley, Wei J. Chen, C. Cloninger, B. Crespo-Facorro, G. Donohoe, R. Freedman, C. Galletly, M. Gandal, M. Gennarelli, D. Hougaard, H. Hwu, A. Jablensky, S. Mccarroll, J. Moran, O. Mors, P. Mortensen, B. Müller-Myhsok, A. Neil, M. Nordentoft, M. Pato, T. Petryshen, M. Pirinen, A. Pulver, T. Schulze, J. Silverman, J. Smoller, E. Stahl, D. Tsuang, E. Vilella, Shi-Heng Wang, Shuhua Xu, R. Adolfsson, C. Arango, B. Baune, S. Belangero, A. Børglum, D. Braff, E. Bramon, J. Buxbaum, D. Campion, J. Cervilla, S. Cichon, D. A. Collier, A. Corvin, D. Curtis, M. Forti, E. Domenici, H. Ehrenreich, V. Escott-Price, T. Esko, A. Fanous, A. Gareeva, M. Gawlik, P. Gejman, M. Gill, S. Glatt, V. Golimbet, K. Hong, C. Hultman, S. Hyman, N. Iwata, E. Jönsson, R. Kahn, James L. Kennedy, E. Khusnutdinova, G. Kirov, J. Knowles, M. Krebs, C. Laurent-Levinson, Jimmy Lee, T. Lencz, D. Levinson, Qingqin S. Li, J. Liu, A. Malhotra, D. Malhotra, A. McIntosh, A. McQuillin, P. Menezes, V. Morgan, D. Morris, B. Mowry, Robin M. Murray, V. Nimgaonkar, M. Nöthen, R. Ophoff, S. Paciga, A. Palotie, C. Pato, Shengying Qin, M. Rietschel, B. Riley, M. Rivera, D. Rujescu, M. C. Saka, A. Sanders, S. Schwab, A. Serretti, P. Sham, Yongyong Shi, D. St. Clair, H. Stefánsson, K. Stefánsson, M. Tsuang, J. van os, M. Vawter, D. Weinberger, T. Werge, D. Wildenauer, Xin Yu, W. Yue, P. Holmans, A. Pocklington, P. Roussos, E. Vassos, M. Verhage, P. Visscher, Jian Yang, D. Posthuma, O. Andreassen, K. Kendler, M. Owen, N. Wray, M. Daly, Hailiang Huang, B. Neale, Patrick F. Sullivan, S. Ripke, J. Walters, M. O’Donovan   +433 more
semanticscholar   +1 more source

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source