Results 41 to 50 of about 45,524 (260)

Extensive mass spectrometry-based analysis of the fission yeast proteome: the Schizosaccharomyces pombe PeptideAtlas [PDF]

, 2013
We report a high quality and system-wide proteome catalogue covering 71% (3,542 proteins) of the predicted genes of fission yeast, Schizosaccharomyces pombe, presenting the largest protein dataset to date for this important model organism.
Aebersold, Alexa, Anderson, Baerenfaller, Beck, Benjamini, Beyer, Bitton, Brockmann, Brunner, Chen, Craig, Davis, de Godoy, de Graaf, Deutsch, Deutsch, Elias, Geer, Ghaemmaghami, Greenbaum, Gygi, Humphrey, Huttlin, Ishihama, Ishihama, Keller, Kuster, Lackner, Lackner, Lam, Lam, Lam, Lam, Marguerat, Mata, Nagaraj, Nesvizhskii, Perkins, Reiter, Remacle, Sakharkar, Savas, Schmidt, Schmidt, Schrimpf, Sherwood, Shevchenko, Shteynberg, Sipiczki, Vizcaíno, Warringer, Wilhelm, Wood, Wood, Wood, Wu, Zhang   +57 more
core   +1 more source

Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins. [PDF]

PLoS ONE, 2016
Telomeres of nuclear chromosomes are usually composed of an array of tandemly repeated sequences that are recognized by specific Myb domain containing DNA-binding proteins (telomere-binding proteins, TBPs).
Regina Sepsiova, Ivona Necasova, Smaranda Willcox, Katarina Prochazkova, Peter Gorilak, Jozef Nosek, Ctirad Hofr, Jack D Griffith, Lubomir Tomaska   +8 more
doaj   +1 more source

Role for the fission yeast RecQ helicase in DNA repair in G2. [PDF]

, 2003
Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3'-to-5' helicase and exists
Ampatzidou, Eleni, Andersen, Anni H, Laursen, Louise V, Murray, Johanne M   +3 more
core   +3 more sources

Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. [PDF]

PLoS ONE, 2011
Prp19 is the founding member of the NineTeen Complex, or NTC, which is a spliceosomal subcomplex essential for spliceosome activation. To define Prp19 connectivity and dynamic protein interactions within the spliceosome, we systematically queried the ...
Liping Ren, Janel R McLean, Tony R Hazbun, Stanley Fields, Craig Vander Kooi, Melanie D Ohi, Kathleen L Gould   +6 more
doaj   +1 more source

Identification of a GTPase-Activating Protein Homolog in Schizosaccharomyces pombe [PDF]

Molecular and Cellular Biology, 1991
Loss of function of the Schizosaccharomyces pombe gap1 gene results in the same phenotypes as those caused by an activated ras1 mutation, i.e., hypersensitivity to the mating factor and inability to perform efficient mating. Sequence analysis of gap1 indicates that it encodes a homolog of the mammalian Ras GTPase-activating protein (GAP). The predicted
Imai, Yoshiyuki, Miyake, Sanae, Hughes, David A., Yamamoto, Masayuki   +3 more
openaire   +4 more sources

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original ...
Lorenz, Alexander, Mehats, Alizée, Osman, Fekret, Whitby, Matthew C   +3 more
core   +1 more source

Engineering ER-stress dependent non-conventional mRNA splicing

eLife, 2018
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Meghan Zubradt, Jonathan S Weissman, Peter Walter   +6 more
doaj   +1 more source

Monitoring Schizosaccharomyces pombe genome stress by visualizing end-binding protein Ku [PDF]

Biology Open, 2021
ABSTRACT Studies of genome stability have exploited visualization of fluorescently tagged proteins in live cells to characterize DNA damage, checkpoint, and repair responses. In this report, we describe a new tool for fission yeast, a tagged version of the end-binding protein Pku70 which is part of the KU protein complex.
Chance E. Jones, Susan L. Forsburg
openaire   +3 more sources

Smc5/6: a link between DNA repair and unidirectional replication? [PDF]

, 2008
Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada, Antony M. Carr, AR Lehmann, B Hu, D Branzei, D Ivanov, DM Sheedy, E Ampatzidou, E Unal, E Unal, EA Andrews, ES Chen, F Onoda, G De Piccoli, GJ Cost, H Morikawa, HB Lindroos, HM Verkade, I Miyabe, J Palecek, J Rouse, J Sergeant, J Torres-Rosell, J Torres-Rosell, JK Chin, Johanne M. Murray, KL Borden, KM Lee, L Strom, L Strom, MI Fousteri, MN Boddy, N Aono, PR Potts, PR Potts, PR Potts, S Pebernard, S Pebernard, SH Harvey, T de Lange, T Kobayashi, T Mengiste, T Morishita, TM Roberts, WH McDonald, WM Thorburn, X Zhao   +46 more
core   +1 more source

Snf1-Like Protein Kinase Ssp2 Regulates Glucose Derepression in Schizosaccharomyces pombe [PDF]

Eukaryotic Cell, 2011
ABSTRACT The function of two fission yeast genes, SPCC74.03c/ ssp2 + and SPAC23H4.02/ ppk9 + , encoding an Snf1-like protein kinase were investigated. Deletion of ssp2 + caused a partial defect in glucose derepression of
Tomohiko Matsuzawa, Yasuko Fujita, Hideki Tohda, Kaoru Takegawa   +3 more
openalex   +3 more sources