Identification of a GTPase-Activating Protein Homolog in Schizosaccharomyces pombe [PDF]
Molecular and Cellular Biology, 1991 Loss of function of the Schizosaccharomyces pombe gap1 gene results in the same phenotypes as those caused by an activated ras1 mutation, i.e., hypersensitivity to the mating factor and inability to perform efficient mating. Sequence analysis of gap1 indicates that it encodes a homolog of the mammalian Ras GTPase-activating protein (GAP). The predicted
Imai, Yoshiyuki +3 more
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BMC Research Notes, 2019 Objectives The fission yeast Schizosaccharomyces pombe is predicted to encode ~ 200 proteins of
Sophie Longmuir +2 more
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Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. [PDF]
PLoS ONE, 2012 The ERH gene encodes a highly conserved small nuclear protein with a unique amino acid sequence and three-dimensional structure but unknown function. The gene is present in animals, plants, and protists but to date has only been found in few fungi.
Marek K Krzyzanowski +2 more
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Tpr1, a Schizosaccharomyces pombe protein involved in potassium transport [PDF]
FEBS Letters, 1999 The Schizosaccharomyces pombe Tpr1 was isolated as suppressor of the Saccharomyces cerevisiae Δ trk1,2 potassium uptake deficient phenotype. Tpr1, for tetratrico peptide repeat, encodes a 1039 amino acid residues protein with several reiterated TPR units displaying significant homology to p150TSP, a recently identified phosphoprotein of mouse, to S ...
Lichtenberg, H, Heyer, M, Höfer, M
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High level constitutive expression of luciferase reporter by lsd90 promoter in fission yeast. [PDF]
PLoS ONE, 2014 Because of a large number of molecular similarities with higher eukaryotes, the fission yeast Schizosaccharomyces pombe has been considered a potentially ideal host for expressing human proteins having therapeutic and pharmaceutical applications. However,
Hemant Kumar Verma +6 more
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The DNA-binding domain of S. Pombe Mrc1 (Claspin) acts to enhance stalling at replication barriers [PDF]
, 2015 Funding: Marie Curie Cancer Care (J.Z. and J.Z.D.), Biotechnology and Biological Sciences Research Council (J.Z.D.) and Cancer Research UK (E.H.) supported this work.During S-phase replication forks can stall at specific genetic loci.
Dalgaard, J.Z. +15 more
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Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe
Cell Division, 2007 Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are required for their function as a putative ...
Okuzaki Daisuke +3 more
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DNA polymerase α (swi7) and the flap endonuclease fen1 (rad2) act together in the s-phase alkylation damage response in S. pombe [PDF]
, 2012 Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching ...
Koulintchenko Milana +20 more
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Gut Pathogens, 2018 Over the years, genetic profiling of the gut microbiome of patients with colorectal cancer (CRC) using genome sequencing has suggested over-representation of several bacterial taxa. However, little is known about the protein or metabolite secretions from
Siok-Fong Chin +3 more
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Suppression of sensitivity to drugs and antibiotics by high external cation concentrations in fission yeast. [PDF]
PLoS ONE, 2015 Potassium ion homeostasis plays an important role in regulating membrane potential and therefore resistance to cations, antibiotics and chemotherapeutic agents in Schizosaccharomyces pombe and other yeasts.
John P Alao +3 more
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