Results 41 to 50 of about 27,508 (229)

Characterization of Schizosaccharomyces pombe Rad2 protein, a FEN-1 homolog [PDF]

Nucleic Acids Research, 1998
FEN-1 proteins are a family of nucleases essential for lagging strand DNA synthesis. A gene with sequence similarity to FEN-1 protein-encoding genes, rad2 +, has been identified in Schizosaccharomyces pombe . We report the overexpression, purification, and character-ization of the putative S.pombe FEN-1 homolog, Rad2p.
J L, Alleva, P W, Doetsch
openaire   +2 more sources

urg1: A Uracil-Regulatable Promoter System for Fission Yeast with Short Induction and Repression Times [PDF]

, 2008
Background. The fission yeast Schizosaccharomyces pombe is a popular genetic model organism with powerful experimental tools. The thiamine-regulatable nmt1 promoter and derivatives, which take > 15 hours for full induction, are most commonly used for ...
Mata, J, Luis López-Maury, Juan Mata, Lopez-Maury, L, Watt, Stephen, Bähler Jürg, Marguerat, Samuel, Mata, Juan, Watt, S, Bahler, J, Gavin Burns, López Maury, Luis, Burns, Gavin, Stephen Watt, Mata Juan, Jürg Bähler, Marguerat, S, Samuel Marguerat, Marguerat Samuel, López-Maury Luis, Burns Gavin, Burns, G, Watt Stephen, Bähler, Jürg Ürg   +23 more
core   +1 more source

Schizosaccharomyces pombe Homologs of Human DJ-1 Are Stationary Phase-Associated Proteins That Are Involved in Autophagy and Oxidative Stress Resistance. [PDF]

PLoS ONE, 2015
The Parkinson's disease protein DJ-1 is involved in various cellular functions including detoxification of dicarbonyl compounds, autophagy and oxidative stress response.
Yang Su, Caiping Chen, Linting Huang, Jianhua Yan, Ying Huang   +4 more
doaj   +1 more source

Interaction of mammalian neprilysin with binding protein and calnexin in Schizosaccharomyces pombe [PDF]

Biochemical Journal, 1999
Neutral endopeptidase (neprilysin or NEP, EC 3.4.24.11) is a zinc metallo-endopeptidase expressed in many eukaryotic cell types and displaying several important physiological roles. In the brain (and central nervous system), this enzyme is involved in the molecular mechanism of pain by its action in the degradation of enkephalin molecules.
H, Beaulieu, A, Elagöz, P, Crine, L A, Rokeach   +3 more
openaire   +2 more sources

Dense Transposon Integration Reveals Essential Cleavage and Polyadenylation Factors Promote Heterochromatin Formation

Cell Reports, 2020
Summary: Heterochromatin functions as a scaffold for factors responsible for gene silencing and chromosome segregation. Heterochromatin can be assembled by multiple pathways, including RNAi and RNA surveillance.
Si Young Lee, Stevephen Hung, Caroline Esnault, Rakesh Pathak, Kory R. Johnson, Oluwadamilola Bankole, Akira Yamashita, Hongen Zhang, Henry L. Levin   +8 more
doaj   +1 more source

Characterization of zfs1 as an mRNA-binding and -destabilizing Protein in Schizosaccharomyces pombe [PDF]

Journal of Biological Chemistry, 2008
Tristetraprolin is a vertebrate CCCH tandem zinc finger protein that can bind to and destabilize certain mRNAs containing AU-rich element binding sites. zfs1 is the single gene in the fission yeast, Schizosaccharomyces pombe, that encodes a protein containing the critical features of the tristetraprolin zinc finger domain.
Brandon J, Cuthbertson, Yanhong, Liao, Lutz, Birnbaumer, Perry J, Blackshear   +3 more
openaire   +2 more sources

The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis [PDF]

, 2013
The spatial and temporal control of polarity is fundamental to the survival of all organisms. Cells define their polarity using highly conserved mechanisms that frequently rely upon the action of small GTPases, such as Ras and Cdc42.
Ladds, Graham, Wayne Croft, Bond, Michael, Croft Wayne, Cathryn Weston, Graham Ladds (430368), Graham Ladds, Cathryn Weston (471448), Croft, Wayne D., Michael Bond, Weston, Cathryn, Ladds Graham, Weston Cathryn, Bond Michael, Michael Bond (471449), Wayne Croft (471450)   +15 more
core   +1 more source

Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. [PDF]

PLoS ONE, 2011
Prp19 is the founding member of the NineTeen Complex, or NTC, which is a spliceosomal subcomplex essential for spliceosome activation. To define Prp19 connectivity and dynamic protein interactions within the spliceosome, we systematically queried the ...
Liping Ren, Janel R McLean, Tony R Hazbun, Stanley Fields, Craig Vander Kooi, Melanie D Ohi, Kathleen L Gould   +6 more
doaj   +1 more source

Engineering ER-stress dependent non-conventional mRNA splicing

eLife, 2018
The endoplasmic reticulum (ER) protein folding capacity is balanced with the protein folding burden to prevent accumulation of un- or misfolded proteins.
Weihan Li, Voytek Okreglak, Jirka Peschek, Philipp Kimmig, Meghan Zubradt, Jonathan S Weissman, Peter Walter   +6 more
doaj   +1 more source

Characterization of Glycoside Hydrolase Family 5 Proteins in Schizosaccharomyces pombe [PDF]

Eukaryotic Cell, 2010
ABSTRACT In yeast, enzymes with β-glucanase activity are thought to be necessary in morphogenetic events that require controlled hydrolysis of the cell wall. Comparison of the sequence of the Saccharomyces cerevisiae exo-β(1,3)-glucanase Exg1 with the Schizosaccharomyces pombe ...
Encarnación, Dueñas-Santero, Ana Belén, Martín-Cuadrado, Thierry, Fontaine, Jean-Paul, Latgé, Francisco, del Rey, Carlos, Vázquez de Aldana   +5 more
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