Results 71 to 80 of about 27,508 (229)
The DNA damage checkpoint: A tale from budding yeast
Frontiers in Genetics, 2022 Studies performed in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have led the way in defining the DNA damage checkpoint and in identifying most of the proteins involved in this regulatory network, which turned out to have structural
Paolo Pizzul +5 more
doaj +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Inhibition of Protein Translocation in Permeabilized Cells ofSchizosaccharomyces pombeby Puromycin [PDF]
Bioscience, Biotechnology, and Biochemistry, 1992 To investigate protein translocation in eukaryotes, we reconstituted a protein translocation system using the permeabilized spheroplasts (P-cells) of the fission yeast Schizosaccharomyces pombe. The precursor of a sex pheromone of Saccharomyces cerevisiae, prepro-alpha-factor, was translocated across the endoplasmic reticulum (ER) of S.
KAMBE-HONJOH, Hideko +2 more
openaire +2 more sources
Journal of FungiCytokinesis, as the last stage of the cell division cycle, is a tightly controlled process amongst all eukaryotes, with defective division leading to severe cellular consequences and implicated in serious human diseases and conditions such as cancer ...
Imane M. Rezig +2 more
doaj +1 more source
The fission yeast XMAP215 homolog Dis1p is involved in microtubule bundle organization. [PDF]
PLoS ONE, 2010 Microtubules are essential for a variety of fundamental cellular processes such as organelle positioning and control of cell shape. Schizosaccharomyces pombe is an ideal organism for studying the function and organization of microtubules into bundles in ...
Hélio Roque +4 more
doaj +1 more source
DNA damage repair proteins across the Tree of Life
iScience, 2023 Summary: Genome maintenance is orchestrated by a highly regulated DNA damage response with specific DNA repair pathways. Here, we investigate the phylogenetic diversity in the recognition and repair of three well-established DNA lesions, primarily ...
Emily Nischwitz +8 more
doaj +1 more source
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
Biological Reviews, EarlyView.ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Characterization of membrane-bound small GTP-binding proteins from Nicotiana tabacum [PDF]
, 1995 Haizel T, Merkle T, Turck F, Nagy F. Characterization of membrane-bound small GTP-binding proteins from Nicotiana tabacum. Plant Physiology.
Haizel, T +7 more
core +1 more source
STAR ProtocolsSummary: Chromatin immunoprecipitation (ChIP) assays provide quantitative information about the genomic localization of chromatin-binding proteins; however, their sensitivity is limited by several technical variables.
Jasbeer S. Khanduja, Mo Motamedi
doaj +1 more source
Cost‐Effective Solid‐State NMR Of Fungal Glucans: A Case Study On Schizosaccharomyces pombe
Chemistry – A European Journal, EarlyView.A cost‐effective solid‐state NMR strategy enables replication and semi‐quantitative assessment of inherent variation of the fungal cell wall. Whole cell and cell wall extractions yield subtly different compositional differences, revealing molecular adaptations invisible to microscopy.
Ananya Singh +3 more
wiley +1 more source