Results 61 to 70 of about 1,097,446 (312)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
School Building Surveying: A Support Tool for School Building Registry Office [PDF]
, 2019 On the national territory, the school building situation appears patchy, with very different situations in several respects, the most important of which is related to structural safety, to possessing the correct certification for fire prevention or hygiene.
Monestiroli, T. +4 more
openaire +4 more sources
Advances in Civil Engineering, 2021 This review presents the existing state-of-the-art practices of indoor environmental quality (IEQ) in naturally ventilated school buildings and is mainly focused on the components of IEQ like thermal comfort, indoor air quality with ventilation, and ...
Nishant Raj Kapoor +6 more
doaj +1 more source
Shuttered Public Schools: The Struggle to Bring Old Buildings New Life [PDF]
, 2013 Large-scale public school closures have become a fact of life in many American cities, and that trend is not likely to stop now. This report looks at what happens to the buildings themselves, studying the experiences of Philadelphia and 11 other cities ...
Emily Dowdall, Susan Warner
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A Study on the Shear Wall Ratio in School Buildings
Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, 2019 Within this current study, in order to be safe of school buildings against an earthquake, shear wall ratio, must have been a plan, was determined depending on floor type.
Hakan ULUTAŞ +3 more
doaj +1 more source
Building Capacity in Struggling Schools [PDF]
Educational Practice and Theory, 2004 The ‘School Facing Exceptionally Challenging Circumstances’ pilot project funded by the DFES includes provision for flexibility in the application of the National Curriculum, a reading programme to support non-fluent readers in Year 7 and Year 8, (i.e.
openaire +1 more source
High Performance School Buildings: Energy-Smart Schools That Make a Difference [PDF]
, 2001 Over seventy percent of U.S. schools still in use today were built before 1960, according to the General Accounting Office. In the next decade, school districts around the nation will have to replace or renovate over six thousand of these buildings, and ...
Susan Ziff
core
Earthquake Science Explained [PDF]
This booklet features a collection of articles originally published for teachers by the San Francisco Chronicle. It presents some of the new understanding gained and scientific advances made in the century since the Great 1906 San Francisco Earthquake ...
core +1 more source