Results 131 to 140 of about 8,777,452 (313)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The Development of COLESTVIAModel as An Effort of Internanalization of Character Values in Social Studies [PDF]
, 2013 Purpose: This research is based on a condition of Social Studies instruction in Junior High schools in Surakarta that is still far from the expectation. It focuses on the cognitive aspect and lack of affective aspects. Therefore, it is important to
Agung S., Leo
core +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Environmental Education should go further [PDF]
, 2000 Outlines Scottish national policy guidelines on 'education for sustainable development' (environmental education for ages 5-14) and implications for primary schools. Describes a 2-year project in which a research team helped staff at an elementary school
Laing, Moira, McNaughton, Marie Jeanne
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Migrant and non-migrant domestic workers in Hanoi: the segmentation of domestic service [PDF]
, 2010 Nguyen M. Migrants and Non-migrant Domestic Workers in Hanoi. The Segmentation of Domestic Service. DEV Working Paper Series. Vol 22.
Nguyen, M.
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Practical strategies to support the whole-school development of AfL with APP (Secondary) [PDF]
, 2009 "This document is intended to help schools make progress with the whole-school development of Assessment for Learning (AfL) by providing examples of approaches and strategies different schools have used." - Page ...
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
, 2009 The spotlight in education in recent years has been focused on the areas of professional development activities for teachers and the development of professional learning communities.
Neuzil, Linda M., Vaughn, Marsha
core