Results 131 to 140 of about 26,250,027 (354)

Beyond the Answers: The Role of Questions in Driving Regional School Development—But Whose Questions and with What Focus?

Trends in Higher Education
School development is important in society. This study investigates how questions work as an information carrier between different levels in a school organization.
Pernilla Granklint Enochson, Jeanette Sjöberg   +1 more
doaj   +1 more source

Safe environments for innovation: developing a new multidisciplinary masters programme [PDF]

, 2010
This paper outlines the research and resulting curriculum design activities conducted as a collaborative venture between Northumbria University’s School of Design, School of Computing, Engineering and Information Sciences and Newcastle Business School ...
Bailey, Mark, Smith, Neil
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Migrant and non-migrant domestic workers in Hanoi: the segmentation of domestic service [PDF]

, 2010
Nguyen M. Migrants and Non-migrant Domestic Workers in Hanoi. The Segmentation of Domestic Service. DEV Working Paper Series. Vol 22.
Nguyen, M.
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Perceptions of Effectiveness of School Counselors with Former Graduates in a TRIO College Program [PDF]

, 2016
The context and variables that affect at-risk students are constantly changing. It is imperative that school counselors understand the risk factors for students and the cultural and social contexts the individual lives within.
Colton, Emily, Cronin, Sarah, Ohrtman, Marguerite, Dr., Thuen, Marin, Torgerson, Erik   +4 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Practical strategies to support the whole-school development of AfL with APP (Secondary) [PDF]

, 2009
"This document is intended to help schools make progress with the whole-school development of Assessment for Learning (AfL) by providing examples of approaches and strategies different schools have used." - Page ...

core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Raum schafft Struktur und Strukturen schaffen Raum

WE_OS-Jahrbuch
Im Artikel wird die Entwicklung der Universitätsschule Dresden (USD) entlang des Ringens um den Schulbau beschrieben. Die USD, welche 2019 als Schulversuchsschule gestartet ist, verfolgt ein innovatives Lernkonzept, das individuelle Entwicklungswege in ...
Anke Langner, Matthias Ritter
doaj   +1 more source