Results 71 to 80 of about 7,340,394 (307)

New School, New Job, New Life

open access: yesJournal of College Orientation, Transition, and Retention, 2011
Student affairs professionals have a responsibility for the professional development of graduate assistants (Gas) in the department as these positions are marketed as first professional positions.
Karen J. Haley   +2 more
doaj   +1 more source

Students at New York Life Revitalizing High School Libraries Sites Talk About Why Their Library Media Centers Rock! [PDF]

open access: yes, 2006
Funded by the New York Life Foundation from 2003-2005, Revitalizing High School Libraries (RHSL) was a pilot program that allowed Public Education Network (PEN) and its member local education funds (LEFs) in Minneapolis, San Francisco and Tampa to update

core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The Beacon Community Centers Middle School Initiative: Final Report on Implementation and Youth Experience in the Initiative [PDF]

open access: yes, 2011
The report evaluates New York City's Beacon Middle School Initiative, which was launched to increase services to middle-grades youth through programs in academics, life skills, career awareness, civic engagement, physical health, and arts and culture ...
Christina A. Russell   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Involved, Invisible, Ignored: The Experiences of Lesbian, Gay, Bisexual and Transgender Parents and Their Children in Our Nation's K-12 Schools [PDF]

open access: yes, 2008
Current estimates suggest there are upwards of 7 million lesbian, gay, bisexual and transgender (LGBT) parents with dependent children in the United States, and it is likely that these numbers have been increasing over recent years.
Elizabeth M. Diaz, Joseph G. Kosciw
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

In memoriam: Professor Kathryn R. Heidt [PDF]

open access: yes, 2006
What is most notable about the life and the career of Professor Kathryn R. Heidt is not that it was tragically cut short by her death on May 24, 2005, but that she was able to achieve so much, both personally and professionally, in the too-brief time ...
Flechtner, Harry M
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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