Results 131 to 140 of about 112,215 (282)

Darboux transformation for the discrete Schrödinger equation [PDF]

open access: green, 2018
Tuncay Aktosun   +2 more
openalex   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch   +7 more
wiley   +1 more source

Engineering of 2‐ketoacid Decarboxylases for Production of Isobutanol and Other Fusel Alcohols in Saccharomyces cerevisiae

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich   +6 more
wiley   +1 more source

Unveiling the Damped Quantum Harmonic Oscillator

open access: yesJurnal Kumparan Fisika
This article dis cusses the often-overlooked "damped" quantum harmonic oscillator, a vibrating system that loses energy over time. We bridge the classical-quantum divide, starting with the familiar equation of motion for a damped oscillator using Hooke's
Yahya Efendi   +2 more
doaj   +1 more source

Optimization of CEST MRI Reporter Protein Design Using Cation‐Pi Networks

open access: yesChemistry – A European Journal, EarlyView.
A novel engineering approach can produce reporter proteins for cell and viral therapy tracking with unique magnetic resonance imaging (MRI) signatures, detectable with chemical exchange saturation transfer (CEST). We discover how cation‐π interactions between amino acid groups can help us fine‐tune magnetic resonance properties for noninvasive ...
David E. Korenchan   +8 more
wiley   +1 more source

Conformational Trajectory of the Molecular Chameleon Grazoprevir from Formulation to Target‐Bound

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Macrocycles represent a promising class of beyond‐rule‐of‐5 (bRo5) therapeutics, capable of targeting proteins traditionally considered undruggable by conventional small molecules. Macrocycles exhibit intrinsic flexibility and often display a “chameleon‐like” ability to adapt to their environment, thereby enhancing their oral bioavailability ...
Lianne H. E. Wieske   +5 more
wiley   +1 more source

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

open access: yesCytoskeleton, EarlyView.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Exact Solutions for a Modified Schrödinger Equation [PDF]

open access: gold, 2019
Yassine Benia   +2 more
openalex   +1 more source

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