Results 151 to 160 of about 91,891 (247)

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Optical soliton solutions of the stochastic generalized nonlinear Schrödinger equation with arbitrary refractive index in Itô sense. [PDF]

Sci Rep
Trouba NT, Xu H, Alngar MEM, Shohib RMA, El-Meligy M, Zhu X, Sharaf M.   +6 more
europepmc   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

The FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao, Hiroshi Otsuka, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Numerical solution of nonlinear Schrödinger equation by a hybrid pseudospectral-variational quantum algorithm. [PDF]

Sci Rep
Köcher N, Rose H, Bharadwaj SS, Schumacher J, Schumacher S.   +4 more
europepmc   +1 more source

Soliton solutions of fractional extended nonlinear Schrödinger equation arising in plasma physics and nonlinear optical fiber. [PDF]

Sci Rep, 2023
Ahmad J, Akram S, Noor K, Nadeem M, Bucur A, Alsayaad Y.   +5 more
europepmc   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

Impact of Brownian motion on the optical soliton solutions for the three component nonlinear Schrödinger equation. [PDF]

Sci Rep
Baber MZ, Shahzad T, Mohammed WW, Ahmed N, Ceesay B, Yasin MW.   +5 more
europepmc   +1 more source

Soliton solution, breather solution and rational wave solution for a generalized nonlinear Schrödinger equation with Darboux transformation. [PDF]

Sci Rep, 2023
Fan C, Li L, Yu F.
europepmc   +1 more source

Dynamics of Gene and Allelic Expression During Modern Hybrid Maize Breeding

Plant Biotechnology Journal, EarlyView.
ABSTRACT Maize breeding has greatly improved yield through single‐cross hybrids, but the underlying gene regulatory changes remain unclear. This study analysed transcriptomes of landmark maize hybrids and their parents across developmental stages and planting densities.
Xuyang Liu, Yongxiang Li, Chunhui Li, Dengfeng Zhang, Guanhua He, Hui Liu, Shumin Sun, Yu Li, Mei Guo, Tianyu Wang   +9 more
wiley   +1 more source

Investigating the stochastic higher dimensional nonlinear Schrodinger equation to telecommunication engineering. [PDF]

Sci Rep
Khan A, Muhammad J, Younas U, Thinakaran R, Abdeljawad T, Alqudah MA.   +5 more
europepmc   +1 more source