Defining the role of αC helix interactions in the activation of the integrin αI domain
The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö +7 more
wiley +1 more source
Investigating the stochastic higher dimensional nonlinear Schrodinger equation to telecommunication engineering. [PDF]
Khan A +5 more
europepmc +1 more source
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
Exploring the chaotic, sensitivity and wave patterns to the dual-mode resonant Schrödinger equation: application in optical engineering. [PDF]
Muhammad J, Younas U, Yar M.
europepmc +1 more source
A chromosome‐level genome of Elcysma westwoodi was assembled. The genome encodes 272 detoxification‐related genes. A single‐copy bCAS was retained for cyanide detoxification. CYP405A and CYP332A were recruited into cyanogenic defence evolution. UGT33A retained a conserved GT‐B fold and catalytic domains.
Minyoung Choi, Murtaza Khan, Juil Kim
wiley +1 more source
Optical solutions to time-fractional improved (2+1)-dimensional nonlinear Schrödinger equation in optical fibers. [PDF]
Murad MAS, Tedjani AH, Li Z, Hussain E.
europepmc +1 more source
Auxin response and PIN‐mediated transport in chlorophyte algae
Like multicellular plants, green algae respond to auxin and move it across their cells. However, their PIN‐like proteins do not act like plant auxin exporters, suggesting that basic auxin transport evolved early and specialized directional transport appeared later in plant evolution.
Adrijana Smoljan +11 more
wiley +1 more source
Explicit solitary wave structure for the stochastic resonance nonlinear Schrödinger equation under Brownian motion with dynamical analysis. [PDF]
Nawaz S +4 more
europepmc +1 more source
The small cyclic peptide CP32 effectively inhibits Phytophthora infestans, the causal agent of potato and tomato late blight. Combined biochemical and phenotypic analyses demonstrate that CP32 disrupts cell wall biosynthesis, a key process in pathogen infection, resulting in a marked reduction of disease symptoms in plants.
Demetrio Marcianò +23 more
wiley +1 more source
Advanced soliton structures and elliptic wave patterns in a sixth-order nonlinear Schrödinger equation using improved modified extended tanh function method. [PDF]
Fahim MM, Ahmed HM, Dib KA, Samir I.
europepmc +1 more source

