Results 161 to 170 of about 91,891 (247)

Structural Elucidation and Engineering of the (S)‐scoulerine 2‐O‐Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song   +14 more
wiley   +1 more source

Laguerre Wavelet Approach for a Two-Dimensional Time-Space Fractional Schrödinger Equation. [PDF]

open access: yesEntropy (Basel), 2022
Bekiros S   +5 more
europepmc   +1 more source

On the Naturalistic Grounds of Grounding

open access: yesRatio, EarlyView.
ABSTRACT This paper examines whether grounding can be naturalized. We adopt a tripartite framework—Ocat (scientific catalogue of existents), Otyp (ontological types), and metaphysics (natures/modal profiles)—and show that classifying as such the relata of putative grounding claims forces a dilemma.
Raoni Arroyo, Jonas R. Becker Arenhart
wiley   +1 more source

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

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