Results 171 to 180 of about 91,891 (247)

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

open access: yeseFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng   +5 more
wiley   +1 more source

Clinicopathological characteristics of patients with inoperable non‐small cell lung cancer harboring circulating NRF2 pathway mutations

open access: yesThe Journal of Pathology, Volume 269, Issue 2, Page 164-181, June 2026.
Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen   +14 more
wiley   +1 more source

The structure of intact and active Photosystem II from Arabidopsis thaliana at 2.44 Å resolution

open access: yesNew Phytologist, Volume 250, Issue 5, Page 3014-3025, June 2026.
Summary Photosystem II (PS II) is a large membrane‐bound protein complex that catalyses light‐driven water oxidation in plants and cyanobacteria. The structure of PS II is well studied in cyanobacteria; however, there are very few PS II structures from plants.
Jack Forsman   +6 more
wiley   +1 more source

Soliton dynamics in optical fiber based on nonlinear Schrödinger equation.

open access: yesHeliyon, 2023
Abdillah Mardi H   +4 more
europepmc   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

open access: yesChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga   +11 more
wiley   +1 more source

Lithium Niobate Quadratic Integrated Nonlinear Photonics: Enabling Ultra‐Wide Bandwidth and Ultrafast Photonic Engines

open access: yesNanophotonics, Volume 15, Issue 9, 13 May 2026.
This perspective surveys emerging quantum and classical photonic applications across operating wavelengths and timescales, highlighting persistent technological gaps in integrated light sources. We examine the unique advantages of quadratic nonlinear photonics on the thin‐film lithium niobate (TFLN) platform and discuss strategies for realizing ...
Meng Tian   +7 more
wiley   +1 more source

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