Results 141 to 150 of about 112,215 (282)
A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands
ChemMedChem, EarlyView.A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova +15 more
wiley +1 more source
Multiplicity of positive solutions for a class of nonlinear Schrödinger equations [PDF]
, 2010 Claudianor O. Alves +1 more
openalex +1 more source
Long time stability of KAM tori for the nonlinear Schrödinger equation [PDF]
, 2021 Xiaolong He, Jia Shi, Xiaoping Yuan
openalex +1 more source
Energy Landscapes in Chemical Reactions and Transport
ChemPhysChem, Volume 26, Issue 6, March 15, 2025.Kinetics/dynamics of chemical reactivity and transport of chemical species in a solid are both determined by the energy landscape in which they take place. Discussing common grounds but also distinct differences may help in advancing the understanding in both fields.
Karl‐Michael Weitzel
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.We present model‐informed selection of the recommended dose for expansion (RDE) of investigational oral ATR inhibitor tuvusertib, by integrating clinical pharmacokinetics (PK), pharmacodynamics (PD), and safety data from DDRiver Solid Tumors 301 trial Part A1 (NCT04170153).
Jatinder Kaur Mukker +20 more
wiley +1 more source
Suprathermal Soliton Solutions to Nonlinear Schrödinger Equation
Contributions to Plasma Physics, EarlyView.ABSTRACT Maxwell distributions are very difficult to find in the low‐pressure environment far away the Earth atmosphere, permeated by high temperatures, various types of radiation, highly energetic particles, space debris, and subjected to microgravity, presenting crucial challenges for spacecraft design and operations, and affecting astronaut's health.
F. E. M. Silveira +2 more
wiley +1 more source
New classes of potentials for which the radial Schrödinger equation can be solved at zero energy: II [PDF]
, 2006 Khosrow Chadan, Reido Kobayashi
openalex +1 more source
Contributions to Plasma Physics, EarlyView.ABSTRACT Warm dense matter (WDM) is a complex state, where quantum effects, thermal excitations, and strong interparticle correlations coexist. Understanding its microscopic composition and medium‐induced modifications of atomic and molecular properties is essential for planetary modeling, fusion research, and high‐energy‐density experiments.
L. T. Yerimbetova +4 more
wiley +1 more source
Are physiological oscillations physiological?
The Journal of Physiology, EarlyView., 2023 Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley +1 more source
TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data
Cytometry Part A, EarlyView.TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou +2 more
wiley +1 more source