Areas of demyelination can be remyelinated by transplanting myelin-forming cells. Schwann cells are the naturally remyelinating cells of the peripheral nervous system and have a number of features that may make them attractive for cell implantation ...
C. M. H. Brierley+6 more
doaj +1 more source
Schwann Cell and Axon Electrical Potential Differences [PDF]
Raimundo Villegas+3 more
openalex +1 more source
Cholinergic and Glutamatergic Axons Differentially Require Glial Support in the Drosophila PNS
In the Drosophila PNS, motor‐ and sensory axons (magenta, green) differentially interact with wrapping glial processes. Sensory axons are more weakly associated with wrapping glia and show a length‐dependent degeneration upon loss of wrapping glia.
Steffen Kautzmann+3 more
wiley +1 more source
Liquid Crystalline Assembly of Collagen for Deterministic Alignment and Spread of Human Schwann Cells [PDF]
Collagen is a key component of the extracellular matrix and well-oriented domains of collagen are relevant for mimicking the local cell environment in vitro. While there has been significant attention directed towards the alignment of collagen, formation of large-scale oriented domains remains a key challenge.
arxiv
Replicator Dynamics of of Cancer Stem Cell; Selection in the Presence of Differentiation and Plasticity [PDF]
Stem cells have the potential to produce lineages of non-stem cell populations (differentiated cells) via a ubiquitous hierarchal division scheme. Differentiation of a stem cell into (partially) differentiated cells can happen either symmetrically or asymmetrically. The selection dynamics of a mutant cancer stem cell should be investigated in the light
arxiv
Investigating the role of SARM1 in central nervous system
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang+4 more
wiley +1 more source
A Study of Quantitative Correlations Between Crucial Bio-markers and the Optimal Drug Regimen of Type-I Lepra Reaction [PDF]
Leprosy (Hansen's) is a disease caused by Mycobacterium leprae. This disease slowly leads to occurrence of leprae reactions which mainly damage peripheral nervous system which cause loss of organs. We can prevent occurring leprae reactions by monitoring the bio-markers involved in it.
arxiv
Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu+9 more
wiley +1 more source
Fibronectin and procollagen produced by a clonal line of Schwann cells [PDF]
Markku Kurkinen, Kari Alitalo
openalex +1 more source
Quality of Life Outcomes in Vestibular Schwannoma: A Prospective Analysis of Treatment Modalities
One of the first prospective cohort studies looks at quality of life (QOL) outcomes for the three main treatment modalities for vestibular schwannoma. In our study, we found comparable long‐term disease‐specific QOL outcomes, which will allow clinicians to more accurately counsel patients before making life‐changing treatment decisions.
A. Hotchkies+14 more
wiley +1 more source