Results 171 to 180 of about 5,296,721 (231)

Red Fluorescent Labeling of Myelin by Membrane‐Targeted tdTomato in Transgenic Mouse Lines

Glia, Volume 74, Issue 12, December 2026.
Transgenic mouse lines expressing membrane‐targeted tdTomato in myelin enable imaging of myelin in the red spectral range. Distinct expression patterns range from wide‐spread labeling to sparse single‐cell resolution, supporting diverse imaging applications.
Anja Reinert, Ulrike Winkler, Sandra Goebbels, Lina Komarek, Wiebke Möbius, Henri Seraf Zanker, Karl Schoknecht, Grit Bornschein, Hartmut Schmidt, Robert Fledrich, Ruth M. Stassart, Petra G. Hirrlinger, Klaus‐Armin Nave, Hauke B. Werner, Aiman S. Saab, Johannes Hirrlinger   +15 more
wiley   +1 more source

<i>DNM2</i>-Charcot-Marie-Tooth neuropathy stems from disrupted Schwann cell function and shows limited therapeutic reversibility. [PDF]

Brain Commun
Goret M, Arbogast T, Laporte J.
europepmc   +1 more source

Cardiovascular Autonomic Neuropathy in Charcot–Marie–Tooth Disease: A Genotype‐Stratified Study of PMP22 Duplication and GJB1 Mutation Carriers

Journal of the Peripheral Nervous System, Volume 31, Issue 4, December 2026.
ABSTRACT Background and Aims Data on cardiovascular autonomic neuropathy (CAN) are sparse in Charcot–Marie–Tooth disease. We aimed to determine the prevalence of CAN in CMT1A and CMTX1 and its associations with neuropathy severity and heart rate variability (HRV), compared with age‐ and sex‐matched controls. Methods Thirty‐six CMT1A, 24 CMTX1 patients,
Kryštof Prášil, Veronika Potočková, Tomáš Nedělka, Alžběta Prášilová, Radim Mazanec   +4 more
wiley   +1 more source

Divergent Schwann cell-immune cell trajectories across vestibular schwannoma subtypes mirror nerve injury-repair programs. [PDF]

J Neuroinflammation
Zhao HG, Wang XP, Zhang J, Ren SK, Liang YC, Li H, Li JM, Zhao XB, Wang LM, Lin YX, Li Z, Zhao F.   +11 more
europepmc   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, Volume 100, Issue 5, Page 1039-1054, November 2026.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Case Report: Schwann cell reprogramming and PDGF-driven nerve hypertrophy in an NF1 patient with CIDP-like autoimmunity. [PDF]

Front Immunol
Wang F, Cao W, Lu J, Huang R, Bai Y, Zhang Y, Wang Z, Chen Z, Wang Z.   +8 more
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Schwann Cell TRPA1, a Proalgesic Ion Channel, Mediates Neuroinflammation and Fibromyalgia-Associated Behaviours in Mice. [PDF]

J Neurochem
Brum ES, Fialho MFP, de Araújo DSM, Landini L, Marini M, De Logu F, Nassini R, Oliveira SM.   +7 more
europepmc   +1 more source

Giant Cervicothoracic Ganglioneuroma Misdiagnosed as Neurofibroma on Core Needle Biopsy: Transcervical Resection and Postoperative Neurological Sequelae: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Ganglioneuroma (GN) may be misdiagnosed as neurofibroma when core needle biopsy samples only contain Schwannian stroma without mature ganglion cells. Even giant cervicothoracic GNs may be resectable through a transcervical approach alone.
Omar Daas, Somaya Al Kiswani, Mohammad Z. Al‐Qaisi, Ahmad Daas, Ashjan Al Shakkah, Sohaib Salahat, Abdullah Nofal   +6 more
wiley   +1 more source

Anti-lipid peroxidation attenuates Schwann cell repair phenotype and attenuates PNI-like behavior in oral squamous cell carcinoma. [PDF]

Transl Cancer Res
Long J, Wang Y, Zou M, Jiang G, Jiang Z, Peng W.   +5 more
europepmc   +1 more source