Electromagnetic exposure changes human Schwann cell motility and transcriptomic profile of hearing-loss-related genes. [PDF]
Mohamed T +5 more
europepmc +1 more source
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor +3 more
wiley +1 more source
Etifoxine drives macrophage M2 polarization via Schwann cell-derived progesterone activation of PPARγ to accelerate peripheral nerve repair. [PDF]
Guo C, Liu S.
europepmc +1 more source
Ancient Schwannoma in the Nasal Cavity—A Rare Case Report With Brief Literature Review
Eye &ENT Research, Volume 3, Issue 3, Page 179-185, September 2026.
Shikhar Chohan +2 more
wiley +1 more source
Molecular Mechanisms of Age‐Related Taste Dysfunction Deciphered by Spatiotemporal Transcriptomics
Multi‐omics profiling reveals that aging impairs stem/progenitor cell differentiation and taste bud regeneration in the posterior tongue. Age‐related macrophage polarization remodeling, marked by the accumulation of pro‐inflammatory M1 macrophages, contributes to a Thbs1‐enriched inhibitory niche that limits taste cell growth and differentiation ...
Wandong Zhao +15 more
wiley +1 more source
Chemogenetic Schwann cell activation impairs early myelination and triggers adult demyelination in the peripheral nervous system. [PDF]
Corral JG +4 more
europepmc +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1-Dependent Signaling Mechanisms. [PDF]
Xu S +12 more
europepmc +1 more source
Blood sTREM2 is emerging as a potential biomarker of neuroinflammation, yet its biological significance remains poorly understood. In this study, plasma sTREM2 was quantified in 547 individuals across Alzheimer's disease, mild cognitive impairment, multiple sclerosis, ATTR polyneuropathy, asymptomatic ATTR mutation carriers, and healthy controls ...
Luisa Agnello +10 more
wiley +1 more source
Safety, efficacy, and distal nerve Schwann cell biodistribution in mice and NHPs to support translation of AAV9 RNAi therapy for CMT1A. [PDF]
Stavrou M +17 more
europepmc +1 more source

