Results 181 to 190 of about 5,296,721 (231)

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

Hypoxia-preconditioned mitochondrial transplantation multidirectionally modulates Schwann cell functions to repair peripheral nerve injury in rats. [PDF]

J Orthop Translat
Dong J, Yan B, Zhao X, Bai J, Shan H, Gao X, Sheng L, Dai J, Jiang F, Zhang M, Bai C, Zhou X, Wei S.   +12 more
europepmc   +1 more source

Claudin‐12‐Expressing Fibroblasts Facilitate Metastatic Spread of Pancreatic Cancer Through Physical Interactions

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived TGF‐β induces CLDN12 expression in cancer‐associated fibroblasts, enabling direct adhesion to pancreatic cancer cells through homophilic CLDN12 interactions, thereby promoting local invasion into adjacent tissues and metastasis to the liver; blockade with C12‐pm suppresses liver metastasis.
Qingcui Li, Xiangjing Miao, Yuanyuan Yang, Ruoyang Chen, Qingqing Fang, Xixi Duan, Xiaohan Lou, Xiaohan Yao, Lijing Zhang, Rainer Glauben, Zhihai Qin, Chen Ni   +11 more
wiley   +1 more source

Cancer Neuroscience: From Hallmark‐Enabling Biology to a Therapeutic Pillar

Advanced Oncology, Volume 1, Issue 1, December 2026.
Moran Amit
wiley   +1 more source

Prenatal Microarray Incidentally Diagnoses a Novel Inherited NF1 Intragenic Duplication

Molecular Genetics &Genomic Medicine, Volume 14, Issue 11, November 2026.
Incidental molecular diagnosis of Neurofibromatosis Type 1 when prenatal chromosome microarray detected a duplication encompassing exons 2–36 of the NF1 gene. Pathogenicity was confirmed by RNA analysis. This case identifies a novel pathogenic NF1 duplication and highlights the importance of clinical genetics referral, pre‐test counseling, and informed
Rhiannon Sandow, Gunjan Garg
wiley   +1 more source

Schwann cell derived extracellular vesicles are multifunctional nanotherapeutic mediators for diabetic oral mucosal wound healing. [PDF]

Discov Nano
Xu Z, Qi H, Zhang X, Qu F, Wu Y, Xu C.
europepmc   +1 more source

Diagnosis and surgical treatment of cutaneous neurofibroma in a goldfish (Carassius auratus)

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A goldfish (Carassius auratus) from a pet store was presented with a nodular lesion on the dorsal cranial region. The fish exhibited normal swimming behaviour and appetite. Clinical evaluation, haematology analysis, and radiography confirmed a superficial cutaneous mass without internal organ involvement.
Luz Zoraya Beatriz Duarte‐Rodriguez, Javier Hernando Albarracín‐Navas, Karen Dayana Prada‐Mejia, John Edinson Avila‐Sandoval, Daniel Leonardo Cala‐Delgado   +4 more
wiley   +1 more source

Graphene Oxide-Modified Titanium Dioxide Nanotubes Promote Schwann Cell Function and Neurotrophic Factor Expression. [PDF]

J Funct Biomater
Cao X, Wang C, Lu R, Mu Y, Hu J, Luo B, Chen S.   +6 more
europepmc   +1 more source

NR4A3 alleviates diabetic neuropathy via GLS2-mediated mitochondrial repair and Schwann cell differentiation. [PDF]

iScience
Pang B, Chen S, Bai Y, Zhang Y, Wang Z.
europepmc   +1 more source

Directional guidance to orient Schwann cell alignment in nerve regeneration requires Plexin-B1. [PDF]

Sci Adv
Li J, Ni H, Halawani D, Estill M, Ramakrishnan A, Alves CJ, Shen L, He X, Friedel RH, Zou H.   +9 more
europepmc   +1 more source