Step I: Screened HR/SMYD4 as key keloid epigenetic genes via bulk/scRNA‐seq and machine learning. Step II: Built a high‐performance nomogram (AUC = 0.988). Step III: Conducted multi‐omics analyses. Step IV: Experimentally verified their differential expression and pathogenic roles.
Yifei Wang +4 more
wiley +1 more source
Few-Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell-Like Phenotypes. [PDF]
Simsar EG +9 more
europepmc +1 more source
f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1. [PDF]
Liu T +5 more
europepmc +1 more source
LIS1 mediated Schwann cell reprogramming enhances perineural invasion by activating the serine/NMDAR/AKT signaling pathway in head and neck squamous carcinoma. [PDF]
Liu J +7 more
europepmc +1 more source
PCSK9 Regulation of Lipid Metabolism in the Nervous System: Implications for Schwann Cell Function and Peripheral Neuropathy. [PDF]
Nowacka A +2 more
europepmc +1 more source
SYK regulates Schwann cell metabolic reprogramming to promote axonal regeneration in immune-mediated neuropathy. [PDF]
Zhang N +5 more
europepmc +1 more source
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity. [PDF]
Gong Z +7 more
europepmc +1 more source
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Recent studies of Schwann cell differentiation in vivo and in vitro have provided new insights into determinative signal transduction events both at the cell surface and in the nucleus. Several polypeptide growth factors and their receptors, most notably the neuregulins and receptors of the ErbB family, have been implicated in the specification of cell
T S, Zorick, G, Lemke
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Schwann cells in neuroblastoma
European Journal of Cancer, 1995Why should we consider Schwann cells when we are interested in the biology of neuroblastomas (NBs)? Although we are familiar with the term "stroma-rich" NB, we basically think of a favourable prognostic subgroup, histologically distinguished by the development of a prominent Schwann cell-stroma.
I M, Ambros, P F, Ambros
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Abstract Theodor Schwann, a German physiologist and one of the founding fathers of cellular theory, was the first to hypothesize the association between myelin (the insulating fatty substance surrounding peripheral nerve axons) and the cells that later took his name.
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