Results 221 to 230 of about 64,431 (291)

Effects of imeglimin on experimental diabetic neuropathy in streptozotocin‐induced diabetic rats

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 951-960, June 2026.
Imeglimin exerted neuroprotective effects in a type 1 diabetic neuropathy model, improving sensory nerve conduction, sciatic nerve blood flow, and intraepidermal nerve fiber density. In vitro, imeglimin promoted neurite outgrowth in a DRG‐derived hybridoma cell line, supporting a direct neurotrophic action.
Wataru Nihei, Ayako Kato, Takuma Sato, Masahiro Yamaguchi, Tatsuhito Himeno, Nobuhisa Nakamura, Kazunori Sango, Keiko Naruse, Jiro Nakamura, Hideki Kamiya, Koichi Kato   +10 more
wiley   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1-Dependent Signaling Mechanisms. [PDF]

Adv Sci (Weinh)
Xu S, He Y, Zou Y, Zhao M, Zhang J, Xu Y, Cai J, Luo X, Ma X, Wu S, Huang Y, Wang X, Guo J.   +12 more
europepmc   +1 more source

Biallelic Nonsense Variants in NEFL May Cause a Non‐Length‐Dependent Neuropathy With Temporal Dispersion on Nerve Conduction Studies

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims Pathogenic variants in NEFL, the gene that encodes the light polypeptide subunit of neurofilaments, are an uncommon cause of autosomal recessive Charcot‐Marie‐Tooth (CMT) disease. In this study, we describe the clinical and electrophysiological features of two families with early‐onset CMT carrying nonsense variants in the ...
Marcus Vinícius Vieira da Silva Gomes, Pedro José Tomaselli, Wilson Marques Jr   +2 more
wiley   +1 more source

Curcumin-Loaded HA-Based Nerve Guidance Conduit with PLA Microfibers-Filled Lumen Enhances Schwann Cell Proliferation and Alignment. [PDF]

ACS Omega
Fuster-Gómez S, Martínez-Férriz A, Navarro-Páez F, Monleón Pradas M.   +3 more
europepmc   +1 more source

A Novel Role of the Perineurium: Evidence for an Essential Function for Macrophage Maintenance and Increase in Isolated Peripheral Nerves

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims It is an established view that the perineurium surrounding peripheral nerves fulfills pivotal barrier functions to protect nerve fibers from noxious agents of the nerve environment. Here we want to investigate whether the perineurium also influences other endoneurial cells, like macrophages.
Miriam Geldermann, Dennis Klein, Eva Maria Weiß, Rudolf Martini   +3 more
wiley   +1 more source

Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration. [PDF]

Aging Cell
Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B.   +8 more
europepmc   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Few-Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell-Like Phenotypes. [PDF]

Adv Healthc Mater
Simsar EG, Cheng P, Dogruel T, Donta M, Jung J, Asante NA, Sakaguchi DS, Mallapragada SK, Kidambi PR, Uz M.   +9 more
europepmc   +1 more source

f-SPION-mediated magnetic stimulation induces reparative Schwann cell reprogramming via cytoskeletal dynamics - gated activation of Piezo1. [PDF]

J Nanobiotechnology
Liu T, Yang M, Tian W, Ren J, Lu L, Wang Y.   +5 more
europepmc   +1 more source

LIS1 mediated Schwann cell reprogramming enhances perineural invasion by activating the serine/NMDAR/AKT signaling pathway in head and neck squamous carcinoma. [PDF]

Cancer Cell Int
Liu J, Dai A, Liu Y, Zhang Y, Yan B, Jin D, Wang F, Gao L.   +7 more
europepmc   +1 more source