Results 221 to 230 of about 49,600 (309)

Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology

Smart Medicine, Volume 4, Issue 3, September 2025.
Conductive nerve conduits featuring oriented topological structures are engineered through ice‐templating technology, utilizing hydrogels and temperature gradients. Such conduits enhance peripheral nerve regeneration by integrating conductivity, aligned architecture, and growth factors, as demonstrated by improved motor recovery in rat models with ...
Hui Zhang, Kaichen Wang, Dongyu Xu, Shuangshuang Miao, Yanhong Dai, Panmiao Liu, Huan Wang   +6 more
wiley   +1 more source

Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis. [PDF]

Nat Commun
Titiz M, Landini L, Souza Monteiro de Araujo D, Marini M, Seravalli V, Chieca M, Pensieri P, Montini M, De Siena G, Pasquini B, Vannuccini S, Iannone LF, Cunha TM, Brancolini G, Bellantoni E, Scuffi I, Mastricci A, Tesi M, Di Tommaso M, Petraglia F, Geppetti P, Nassini R, De Logu F.   +22 more
europepmc   +1 more source

Unusual Morphologic Presentation of Perineural Spread From Cutaneous Squamous Cell Carcinoma: Diagnosis Aided by Comprehensive Molecular Analysis and Machine Learning

Journal of Cutaneous Pathology, Volume 52, Issue 9, Page 568-573, September 2025.
ABSTRACT Neoplasms of unknown primary frequently pose a diagnostic challenge due to their nonspecific morphological and immunohistochemical features. Definitive classification of these neoplasms has a profound impact on treatment decisions. Mutational and gene expression profiling can provide diagnostic and prognostic information in these challenging ...
Madhurya Ramineni, Hassan Ghani, Bruce R. Smoller, Rajnish Bharadwaj   +3 more
wiley   +1 more source

Amniotic fluid stem cell conditioned medium's role in Schwann cell proliferation, survival, and cellular antioxidant activity under normative and oxidative stress conditions. [PDF]

Ann Transl Med
Gwam C, Mohamed N, Ogunsola AS, Brown MG, Henry KA, Ma X.   +5 more
europepmc   +1 more source

Mechanistic insights into dental stem cells‐derived exosomes in regenerative endodontics

International Endodontic Journal, Volume 58, Issue 9, Page 1384-1407, September 2025.
Abstract Background Dental pulp is a richly vascularised and innervated tissue vital for tooth vitality, sensory function, and structural integrity. While conventional root canal therapy effectively treats necrotic permanent teeth, it irreversibly eliminates pulp vitality, potentially increasing the risk of secondary infections and long‐term structural
Paras Ahmad, Nathan Estrin, Nima Farshidfar, Yufeng Zhang, Richard J. Miron   +4 more
wiley   +1 more source

Tau Isoform-Regulated Schwann Cell Proliferation and Migration Improve Peripheral Nerve Regeneration After Injury. [PDF]

Int J Mol Sci
Li S, Zhang F, Wang G, Liu Q, Wang X, Chen Q, Chu D.   +6 more
europepmc   +1 more source

Extracellular vesicles from pancreatic cancer and its tumour microenvironment promote increased Schwann cell migration. [PDF]

Br J Cancer
Wong FC, Merker SR, Bauer L, Han Y, Le VMH, Wenzel C, Böthig L, Heiduk M, Drobisch P, Rao VS, Malekian F, Mansourkiaei A, Sperling C, Polster H, Pecqueux M, Istvanffy R, Ye L, Kong B, Aust DE, Baretton G, Seifert L, Seifert AM, Weitz J, Demir IE, Kahlert C.   +24 more
europepmc   +1 more source

Imeglimin improves hyperglycemia and hypoglycemia‐induced cell death and mitochondrial dysfunction in immortalized adult mouse Schwann IMS32 cells

Journal of Diabetes Investigation, Volume 16, Issue 9, Page 1586-1596, September 2025.
Imeglimin reduces Schwann cell death by suppressing Complex I and oxidative stress, which may prevent diabetic neuropathy by protecting mitochondrial functions. ABSTRACT Aims/Introduction Imeglimin, a novel oral antidiabetic drug, enhances glucose‐stimulated insulin secretion, improves insulin sensitivity, and reduces mitochondrial reactive oxygen ...
Ayako Kato, Wataru Nihei, Hideji Yako, Yasuaki Tatsumi, Tatsuhito Himeno, Masaki Kondo, Yoshiro Kato, Jiro Nakamura, Hideki Kamiya, Kazunori Sango, Koichi Kato   +10 more
wiley   +1 more source

Selective RNAi silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury. [PDF]

Mol Ther Methods Clin Dev
Itson-Zoske B, Gani U, Mikesell A, Qiu C, Fan F, Stucky CL, Hogan QH, Shin SM, Yu H.   +8 more
europepmc   +1 more source

Clinical value of high‐frequency ultrasound and serum miR‐92a‐3p in diabetic peripheral neuropathy

Journal of Diabetes Investigation, Volume 16, Issue 9, Page 1692-1703, September 2025.
Serum miR‐92a‐3p and CSAs of median, ulnar, and tibial nerves are elevated in DPN patients. Their combination has high diagnostic significance in identifying DPN in T2DM patients and assessing its severity. ABSTRACT Aims/Introduction Cross‐sectional area (CSA) by high‐frequency ultrasound (HF‐US) detects morphologic changes in neuropathy. microRNA (miR)
Chunmei Qiao, Zhenjiao Liu, Boran Wang, Xin Wang, Zifu Zhao, Hui Wang, Xiaolei Wang   +6 more
wiley   +1 more source