Correlated disorder in myelinated axons orientational geometry and structure [PDF]
While the ultrastructure of the myelin has been considered to be a quasi-crystalline stable system, nowadays its multiscale complex dynamics appears to play a key role for its functionality, degeneration and repair processes following neurological diseases and trauma.
arxiv +1 more source
In the present study, the effects of hyaluronic acid (HA) combined with chitosan conduit on peripheral nerve scarring and regeneration were investigated in a rat model of peripheral nerve crush injury.
Runxin Li+11 more
semanticscholar +1 more source
Immune cell distribution and immunoglobulin levels change following sciatic nerve injury in a rat model [PDF]
Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly ...
Wei Yuan, Xinhong Feng
doaj
Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]
Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F.+1 more
core +1 more source
Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush
Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion is known to be an essential trigger of the pathological changes that have a critical ...
E. Gugliandolo+8 more
semanticscholar +1 more source
Interleukin 6/gp130 axis promotes neural invasion in pancreatic cancer
Nerve invasion (N‐inv) is an important prognostic factor in pancreatic ductal adenocarcinoma (PDAC). To elucidate circulating stimulators for nerve invasion, the authors evaluated the stimulant activity and the inhibitory effects of IL‐6/gp130 axis. Biological activity of IL‐6/gp130 axis promoted nerve invasion in murine model and was upregulated in ...
Hidetaka Suzuki+9 more
wiley +1 more source
Endoscopic Sciatic Neurolysis for Deep Gluteal Space Syndrome
Background: Deep gluteal syndrome (DGS) encompasses a spectrum of pathologies causing symptomatic sciatic nerve compression deep to the gluteus maximus muscle.
Nicholas A. Trasolini MD+3 more
doaj +1 more source
The present study aimed to describe the ultrasonography technique and analyze the ultrasonographic findings of the proximal sciatic nerve and deep gluteal muscles in dogs with suspected sciatic neuritis.
Tiiu M. Toijala+2 more
doaj +1 more source
RP-CARS reveals molecular spatial order anomalies in myelin of an animal model of Krabbe disease [PDF]
Krabbe disease (KD) is a rare demyelinating sphingolipidosis, often fatal in the first years of life. It is caused by the inactivation of the galactocerebrosidase (GALC) enzyme that causes an increase in the cellular levels of psychosine considered to be at the origin of the tissue-level effects.
arxiv +1 more source
The potential role of sciatic nerve stiffness in the limitation of maximal ankle range of motion
It is a long held belief that maximal joint range of motion (ROM) is restricted by muscle tension. However, it exists indirect evidence suggesting that this assumption may not hold true for some joint configurations where non-muscular structures, such as
R. Andrade+7 more
semanticscholar +1 more source