Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
, 2015 Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources
Immune cell distribution and immunoglobulin levels change following sciatic nerve injury in a rat model [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly ...
Wei Yuan, Xinhong Feng
doaj
A Rabbit Model for Peripheral Nerve Reconstruction Studies Avoiding Automutilation Behavior
Journal of Brachial Plexus and Peripheral Nerve Injury, 2022 Background The rabbit sciatic nerve injury model may represent a valuable alternative for critical gap distance seen in humans but often leads to automutilation. In this study, we modified the complete sciatic nerve injury model for avoiding autophagy.
Jonathan A. Sorkin +6 more
doaj +1 more source
Examining the mechanical influences upon the sciatic nerve at the sciatic nerve-hamstring muscle interface during active and passive knee extension [PDF]
, 2015 Background: Ultrasound imaging has been used to examine movement of the peripheral nervous system in response to normal body movements and therapeutic exercises, such as neural mobilisation.
Ellis, R +4 more
core +1 more source
Molecular Medicine Reports, 2018 In the present study, the effects of hyaluronic acid (HA) combined with chitosan conduit on peripheral nerve scarring and regeneration were investigated in a rat model of peripheral nerve crush injury.
Runxin Li +11 more
semanticscholar +1 more source
RP-CARS reveals molecular spatial order anomalies in myelin of an animal model of Krabbe disease [PDF]
Journal of Biophotonics 10 (2017) 385-393, 2020 Krabbe disease (KD) is a rare demyelinating sphingolipidosis, often fatal in the first years of life. It is caused by the inactivation of the galactocerebrosidase (GALC) enzyme that causes an increase in the cellular levels of psychosine considered to be at the origin of the tissue-level effects.
arxiv +1 more source
Cement burn of the sciatic nerve [PDF]
The Journal of Bone and Joint Surgery. British volume, 1992 We present the case of a 63-year-old woman who sustained an acrylic cement burn of the sciatic nerve at hip replacement. She was treated by resection of the damaged segment and grafting. Electron microscopy showed that the nerve was nearly normal 1 cm from the cement margin indicating that this is a safe level for resection.
Rolfe Birch +3 more
openaire +3 more sources
The potential role of sciatic nerve stiffness in the limitation of maximal ankle range of motion
Scientific Reports, 2018 It is a long held belief that maximal joint range of motion (ROM) is restricted by muscle tension. However, it exists indirect evidence suggesting that this assumption may not hold true for some joint configurations where non-muscular structures, such as
R. Andrade +7 more
semanticscholar +1 more source
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
core +2 more sources
Sciatic nerve injury related to hip replacement surgery: imaging detection by MR neurography despite susceptibility artifacts. [PDF]
PLoS ONE, 2014 Sciatic nerve palsy related to hip replacement surgery (HRS) is among the most common causes of sciatic neuropathies. The sciatic nerve may be injured by various different periprocedural mechanisms.
Marcel Wolf +7 more
doaj +1 more source