Background Although autologous nerve grafting is the gold standard treatment of peripheral nerve injuries, several alternative methods have been developed, including nerve conduits that use supportive cells. However, the seeding efficacy and viability of
Hirofumi Yurie+12 more
semanticscholar +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Clinical importance of anatomical variants of sciatic nerve in relation to the piriformis muscle
Background and aims: The sciatic nerve usually emerges below the Piriformis muscle. Each anatomical variant of sciatic nerve is associated with a specific clinical presentation.
Rashmi Deopujari+2 more
doaj +1 more source
Postoperative pain and morphine consumption after ultrasound-guided femoral and sciatic combined nerve block versus neurostimulation for femoral and sciatic combined nerve block or neurostimulation for femoral nerve block in primary elective total knee arthroplasty. [PDF]
Congreso XXXVII National Meeting of the Spanish Society of Pharmacology with guest society: The British Pharmacological SocietyBackground and Aims: Total knee arthroplasty injuries are extremely painful and merit prompt attention to adequate ...
Bellido-Estevez, Inmaculada+3 more
core
Sciatic Nerve Injury After Proximal Hamstring Avulsion and Repair
Background: Muscle bellies of the hamstring muscles are intimately associated with the sciatic nerve, putting the sciatic nerve at risk of injury associated with proximal hamstring avulsion.
T. Wilson+4 more
semanticscholar +1 more source
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu+7 more
wiley +1 more source
Sciatic nerve injury related to hip replacement surgery: imaging detection by MR neurography despite susceptibility artifacts. [PDF]
Sciatic nerve palsy related to hip replacement surgery (HRS) is among the most common causes of sciatic neuropathies. The sciatic nerve may be injured by various different periprocedural mechanisms.
Marcel Wolf+7 more
doaj +1 more source
Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy : pain relief and neuroprotection share a PPAR-alpha-mediated mechanism [PDF]
Peer reviewedPublisher ...
Calignano, A+6 more
core +4 more sources
Peripheral nervous system owns the ability of self-regeneration, mainly in its regenerative microenvironment including vascular network reconstruction. More recently, more attentions have been given to the close relationship between tissue regeneration ...
Hongkui Wang+7 more
semanticscholar +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source