Results 41 to 50 of about 23,100 (268)

Diabetic Peripheral Neuropathy Increases Electrical Stimulation Threshold of Sciatic Nerve: A Prospective Parallel Cohort Study

Diabetes, Metabolic Syndrome and Obesity, 2020
Guang Ying Zhang, Yi Feng Chen, Wei Xin Dai, Dan Zhang, Yi Huang, Wen Zheng He, Cheng Xin Lin Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of ChinaCorrespondence: Cheng Xin ...
Zhang GY, Chen YF, Dai WX, Zhang D, Huang Y, He WZ, Lin CX   +6 more
doaj  

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Leptin-deficient ob/ob mice are a model of type 2 diabetes induced peripheral neuropathy. Ob/ob mice exhibit obesity, insulin resistance, hyperglycaemia, and alterations of peripheral nerve fibres and endoneural microvessels. Here we test the
Joanna Kosacka, Marcin Nowicki, Nora Klöting, Matthias Kern, Michael Stumvoll, Ingo Bechmann, Heike Serke, Matthias Blüher   +7 more
doaj   +1 more source

Sciatic Neuropathy Associated With Persistent Sciatic Artery

Archives of Neurology, 1992
Persistent sciatic artery is a congenital vascular anomaly of the arterial supply to the lower extremity. Thrombosis, distal embolization, aneurysmal dilatation, and rupture of this vessel with compression of the sciatic nerve have been recorded.
Gasecki, A, Ebers, G, Vellet, A, Buchan, A   +3 more
openaire   +2 more sources

Glial βii spectrin contributes to paranode formation and maintenance [PDF]

, 2018
Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D., Chang, Kae Jiun, Dupree, Jeffrey L., Galiano, Mauricio Raul, Griggs, Ryan B., Huang, Claire Yu Mei, Liu, Yanhong, Rasband, Matthew N., Susuki, Keiichiro, Tsai, Chang Ru, Yermakov, Leonid M., Zhang, Chuansheng, Zollinger, Daniel R.   +12 more
core   +1 more source

Sciatic Neuropathy: Case Report and Discussion of the Literature on Postoperative Sciatic Neuropathy and Sciatic Nerve Tumors [PDF]

HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery, 2006
Sciatic nerve injury and dysfunction is not an uncommon cause of lower extremity symptoms in a musculoskeletal practice. We present the case of a man who presented with lower extremity weakness, pain, and cramps, and was initially diagnosed at an outside institution with bilateral S1 radiculopathies and recommended for spine surgery. He came to us for
Joseph, Feinberg, Shikha, Sethi
openaire   +2 more sources

Is resistance to ischaemia of motor axons in diabetic subjects due to membrane depolarization? [PDF]

, 1990
The reasons for the resistance to ischaemia of peripheral nerves in diabetics are not well understood. We have now explored whether axonal depolarization underlies this phenomenon, as has previously been proposed.
Baker, Barrett, Bergmans, Bergmans, Bostock, Das, Dyck, Gilliat, Greene, Gregersen, Horowitz, Hugh Bostock, Jaramillo, Klaus Piwernetz, Low, Low, Ludin, Masson, Michael Strupp, Newrick, Oh, Parry, Paul Weigl, Peter Grafe, Ritchie, Rolf Renner, Shirabe, Steiness, Steiness, Steiness, Strupp, Stöhr, Thomas, Tuck, Weigl   +34 more
core   +1 more source

Galanin and its receptor system promote the repair of injured sciatic nerves in diabetic rats

Neural Regeneration Research, 2016
Various studies have reported that galanin can promote axonal regeneration of dorsal root ganglion neurons in vitro and inhibit neuropathic pain. However, little is known about its effects on diabetic peripheral neuropathy, and in vivo experimental data ...
Xiao-feng Xu, Dan-dan Zhang, Jin-chi Liao, Li Xiao, Qing Wang, Wei Qiu   +5 more
doaj   +1 more source

Schwann cell-derived exosomes ameliorate peripheral neuropathy induced by ablation of dicer in Schwann cells

Frontiers in Cellular Neuroscience
BackgroundMicroRNAs (miRNAs) in Schwann cells (SCs) mediate peripheral nerve function. Ablating Dicer, a key gene in miRNA biogenesis, in SCs causes peripheral neuropathy.
Lei Wang, XueRong Lu, Alexandra Szalad, Xian Shuang Liu, Yi Zhang, Xinli Wang, William Anthony Golembieski, Brianna Powell, Mikkala Mccann, Mei Lu, Michael Chopp, Michael Chopp, Zheng Gang Zhang   +12 more
doaj   +1 more source

Delayed Presentation of Sciatic Nerve Injury after Total Hip Arthroplasty: Neurosurgical Considerations, Diagnosis, and Management

Journal of Neurological Surgery Reports, 2016
Background Total hip arthroplasty (THA) is an established treatment for end-stage arthritis, congenital deformity, and trauma with good long-term clinical and functional outcomes.
Linda W. Xu, Anand Veeravagu, Tej D. Azad, Ciara Harraher, John K. Ratliff   +4 more
doaj   +1 more source

Montelukast reduced docetaxel-induced peripheral neuropathy in rats by altering oxidative stress, histopathological damage, and gene expressions [PDF]

Brazilian Journal of Medical and Biological Research
Peripheral neuropathy (PN) is a common side effect of docetaxel (DTX). In this study, we aimed to evaluate the effects of montelukast (MNT), a leukotriene receptor antagonist drug, against DTX-induced PN in rats.
M.D. Karakoç, Ö. Özmen, M.N. Zengin, O. Çiftçi   +3 more
doaj   +1 more source