Results 41 to 50 of about 220,539 (258)

Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice

Neurobiology of Disease, 2012
Peripheral neuropathy is one of the most common complications of diabetes mellitus. Using a mouse model of diabetic peripheral neuropathy, we tested the hypothesis that thymosin β4 (Tβ4) ameliorates diabetes‐induced neurovascular dysfunction in the ...
Lei Wang, Michael Chopp, Alexandra Szalad, Zhongwu Liu, Mei Lu, Li Zhang, Jing Zhang, Rui Lan Zhang, Dan Morris, Zheng Gang Zhang   +9 more
doaj   +1 more source

Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy : pain relief and neuroprotection share a PPAR-alpha-mediated mechanism [PDF]

, 2013
Peer reviewedPublisher ...
Calignano, A, D'Agostino, G, Di Cesare Mannelli, L, Ghelardini, C, Pacini, A, Russo, R, Zanardelli, M   +6 more
core   +4 more sources

The clinical features of the piriformis syndrome: a systematic review [PDF]

, 2010
Piriformis syndrome, sciatica caused by compression of the sciatic nerve by the piriformis muscle, has been described for over 70 years; yet, it remains controversial. The literature consists mainly of case series and narrative reviews. The objectives of
A Chantraine, A Hulbert, A Ku, A Miller, AG Filler, AH Freiberg, AH Freiberg, AJ Sutton, AM Lewis, B Gandhavadi, B Kumar, BSE Rich, C Steiner, CC Stegbauer, CE Dionne, CW Chang, CW Slipman, D Pokorny, D West, DA Jabs, DL Kent, DR Robinson, E Ernst, E Ernst, E Ernst, E Ernst, EC Papadopoulos, EC Yuen, EM Raney, ER Benson, EW Retzlaff, EY Lee, F Cramp, Fujian Song, G Waddell, GM Wyant, H Nakamura, HF Guyomarc’h, HI Pecina, HT Benzon, HW Park, I Colmegna, I Kosukegawa, IM Merlo, J Dalmau-Carola, J Karppinen, J Kouvalchouk, J Soga, J Young, JA Adams, JA Brown, JB Pace, JD Stewart, JJ Jankiewicz, JK Silver, JP Vandenbroucke, JS Kirschner, JWT Byrd, K Hopayian, K Indrekvam, K Konstantinou, Kevork Hopayian, KJ Stevens, KW Chong, L Jroundi, LF Solheim, LM Fishman, LM Fishman, LM Fishman, M Hanania, M Jenicek, M Pecina, M Tulder van, MC Vallejo, ME Julsrud, MR Foster, MR Foster, MW Cook, N Mayrand, NA Broadhurst, OA El Rubaidi, P Kobbe, P Limongelli, P Rossi, PM Barton, PM Bossuyt, R Dhote, RA Beatty, RD Karl Jr, Ricardo Riera, RJ Spinner, RL Tiel, RL Tiel, RP Beauchesne, RP Hallin, RR Richardson, S Bustamante, S Ozaki, S Turtas, SC Sayson, Sidha Sambandan, SJ Yoon, SM Papadopoulos, SM Papadopoulos, SS Hughes, T Banerjee, T Rodrigue, TN Bernard, TS Carey, V Rucco, VM Synek, VM Synek, WJ Mixter, WP Vandertop, WS Chen, WS Chen, WS Chen, Z Durrani   +117 more
core   +2 more sources

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]

, 2015
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky, Demon, Dieter, Janssens, Sophie, Lamkanfi, Mohamed, Lornet, Guillaume, Timmerman, Vincent, Ydens, Elke   +6 more
core   +2 more sources

Recurrent diffuse large B-cell lymphoma involving the sciatic nerve: A rare case report and review of the literature

Journal of Medical Sciences, 2020
Neurolymphomatosis (NL) is an uncommon condition involving lymphomatous invasion of the cranial or spinal nerve roots. Sciatic nerve neuropathy and dysfunction represent a common cause of lower extremity symptoms in clinical practice.
Chun-Yi Lee, Tsung-Yen Ho, Yung-Tsan Wu, Liang-Cheng Chen, Tsung-Ying Lee   +4 more
doaj   +1 more source

Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]

, 2018
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A., Cunningham, Madeleine E., Gourlay, Dawn, Halstead, Susan K., McGonigal, Rhona, Meehan, Gavin R., Wang, Yuzhong, Willison, Hugh J., Yao, Denggao   +8 more
core   +1 more source

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy [PDF]

, 2017
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent of ...
Asadollahi, Ebrahim, Baes, Myriam, Blanz, Judith, Brügger, Britta, de Hoz, Livia, Kassmann, Celia Michèle, Kleinecke, Sandra, Kungl, Theresa, Lüchtenborg, Christian, McGonigal, Rhona, Möbius, Wiebke, Naseri, Kobra, Nave, Klaus-Armin, Quintes, Susanne, Richert, Sarah, Sachsenheimer, Timo, Sereda, Michael W., Willison, Hugh   +17 more
core   +3 more sources

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter, Niedermeier, W., Schneider, Uwe   +2 more
core   +1 more source

Nerve damage induced skeletal muscle atrophy is associated with increased accumulation of intramuscular glucose and polyol pathway intermediates [PDF]

, 2020
Perturbations in skeletal muscle metabolism have been reported for a variety of neuromuscular diseases. However, the role of metabolism after constriction injury to a nerve and the associated muscle atrophy is unclear.
Afzal, Shoaib, Kempa, Stefan, Langer, Henning Tim, Spuler, Simone   +3 more
core   +2 more sources

Metformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway [PDF]

Archives of Endocrinology and Metabolism
Objective: Diabetic neuropathy (DN) is an important complication of diabetes mellitus. Autophagy is considered to be potentially involved in the regulation of DN. Metformin is broadly utilized in the first-line treatment of diabetes.
Fangqin You, Diya Xie, Cheng Li, Lihang Yang, Fengmin Liu   +4 more
doaj   +1 more source