Results 161 to 170 of about 192,238 (309)

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

open access: yesSmall Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli   +6 more
wiley   +1 more source

Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate [PDF]

open access: yes, 1994
Cook, Deborah R.   +8 more
core   +1 more source

Exercise in Pregnancy and Risk of Postpartum Depression: A Randomised Controlled Trial

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate whether regular aerobic exercise during pregnancy reduces the incidence of postpartum depression in women with low‐risk singleton pregnancies. Design Single‐centre randomised controlled trial. Setting Department of Obstetrics and Gynaecology, University of Naples Federico II, Italy.
Gabriele Saccone   +6 more
wiley   +1 more source

Gene therapy of destructive arthritis in SCID mice [PDF]

open access: diamond, 2003
Ulrich Sack   +8 more
openalex   +1 more source

Prenatal alcohol exposure increases the aggressiveness of estrogen‐induced pituitary tumors in male rats

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Prenatal alcohol exposure (PAE) enhances the development of aggressive pituitary tumors (PitNETs) in female rats. In this study, we found that PAE also promotes the development of PitNETs in male rats. Like in females, PAE treatment enhances the expression of stem cell and tumor aggressiveness genes and increases tumor cell proliferation rate ...
Shaista Chaudhary, Dipak K. Sarkar
wiley   +1 more source

An Atypical Severe Combined Immunodeficiency (SCID) Case Diagnosis Complicated by Alternative Care in the Era of Newborn Screening (NBS) for SCID [PDF]

open access: bronze, 2017
Taylor Alberdi   +22 more
openalex   +1 more source

Variations in alcohol craving and negative mood during a clinical trial of ibudilast for alcohol use disorder

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Neuroimmune compounds are being investigated as novel treatments for alcohol use disorder (AUD). This secondary analysis of a randomized clinical trial of ibudilast for AUD (N = 102) evaluated changes in self‐report symptom measures of craving, depression, and anxiety collected monthly over 12 weeks.
Lindsay R. Meredith   +3 more
wiley   +1 more source

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