Results 141 to 150 of about 102,493 (259)

Integrative methylation and miRNA dysregulation in dlPFC reveal distinct molecular signatures of suicide and non‐suicide subtypes in major depressive disorder

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim Major depressive disorder (MDD) is a leading cause of disability and carries a high risk of suicide. MicroRNAs (miRNAs) are epigenetic regulators implicated in MDD and can be regulated by DNA methylation, potentially reshaping downstream gene networks.
Aleena Francis, Yogesh Dwivedi
wiley   +1 more source

Characterizing social motivation deficits in treatment‐resistant schizophrenia: Evidence from social incentive performance

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui   +11 more
wiley   +1 more source

BCG arthritis in a patient with Severe Combined Immunodeficiency Disorder (SCID): a case report. [PDF]

open access: yesBMC Pediatr
Eskandarzadeh S   +4 more
europepmc   +1 more source

The bodily self in fibromyalgia: A systematic review and meta‐analysis of body image, body representation, and interoceptive dysfunction

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Fibromyalgia is a complex chronic pain condition associated with widespread symptoms and perceptual distortions beyond nociception. Alterations in body image, body representation, and interoception may contribute to symptom severity and reduced quality of life. This review synthesizes evidence related to body image in adults with fibromyalgia.
Martina Mesce   +5 more
wiley   +1 more source

IL2RG-related immunodeficiencies: from SCID to atypical presentations. [PDF]

open access: yesFront Immunol
Briassouli E   +3 more
europepmc   +1 more source

The role of acquired host immunity in periodontal diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane   +2 more
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

Treosulfan-fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study. [PDF]

open access: yesBr J Haematol
Lum SH   +15 more
europepmc   +1 more source

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