Results 161 to 170 of about 187,417 (303)

Gene therapy for B-cell lymphoma in a SCID mouse model using an immunoglobulin-regulated diphtheria toxin gene delivered by a novel adenovirus-polylysine conjugate [PDF]

, 1994
Cook, Deborah R., Curiel, David T., Curiel, Tyler J., Glode, L. M., Maxwell, F., Maxwell, I. H., Purner, M. B., Stevens, J. O., Wagner, Ernst   +8 more
core   +1 more source

On the SCIDs? [PDF]

Nature, 1989
D E, Mosier, R J, Gulizia, S M, Baird, D B, Wilson   +3 more
openaire   +2 more sources

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Relationship between emotional competence, dissociative symptoms and borderline personality disorder traits in female adolescents engaging in non-suicidal self-injury. [PDF]

Child Adolesc Psychiatry Ment Health
Otto A, Jacob R, Jarvers I, Kandsperger S, Brunner R.   +4 more
europepmc   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

Midgestational injection of highly expanded human CD34+ cells increases lineages of human immune cells and supports thymic development in <i>RAG2-/-IL2RG-/Y</i> SCID pigs. [PDF]

Front Immunol
Forster AM, Kress AA, Kiupel M, Cunnick J, Webster DA, Campbell JM, Watson AL, Gafni O, Carlson DF, Moriarity BS, Webber BR, Napiwocki B, Daharsh L, Ross JW, Sauer MB, Tuggle CK.   +15 more
europepmc   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

General Dementia Training for the Social Care Workforce: A Systematic Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim The aim of this systematic review was to assess and synthesize the global evidence on existing general dementia training and education for the social care workforce. Design Mixed‐methods systematic review. Data Sources Systematic searches on five databases (PubMed, APA PsychINFO, CINAHL Plus, Scopus, Web of Science) were conducted for ...
Clarissa Giebel, Thais Caprioli, Marie Poole, Catherine Talbot, Jacqui Cannon, Kerry Hanna, Louise Robinson, Deborah Rozansky, Hilary Tetlow, Madeleine Walpert, Mark Gabbay   +10 more
wiley   +1 more source

An update on inborn errors of V(D)J recombination. [PDF]

Physiology (Bethesda)
Schim van der Loeff I, Ahuja M, Chen R, Patane E, Hambleton S.   +4 more
europepmc   +1 more source

SCID Mouse [PDF]

, 2020
openaire   +1 more source