Results 11 to 20 of about 187,417 (303)
Медицинская иммунология, 2017 Neonatal screening for primary immunodeficiencies (PID) provides a unique opportunity for early detection of moderate to severe immune disorders. Thus, the patients could be provided with best available therapy, due to effective treatment according to ...
I. A. Korsunskiy +5 more
doaj +1 more source
Cognitive behavioral group therapy versus psychoeducational intervention in Parkinson's disease [PDF]
, 2018 Objective: The aim of the current study was to evaluate whether cognitive behavioral group therapy has a positive impact on psychiatric, and motor and non-motor symptoms in Parkinson’s disease (PD).
Berardelli, Isabella +7 more
core +2 more sources
Development of a Multiplex Real-Time PCR Assay for the Newborn Screening of SCID, SMA, and XLA
International Journal of Neonatal Screening, 2019 Numerous studies have shown evidence supporting the benefits of universal newborn screening for primary immunodeficiencies (PID) and for Spinal Muscular Atrophy (SMA).
Cristina Gutierrez-Mateo +12 more
doaj +1 more source
Fludarabine as a cost-effective adjuvant to enhance engraftment of human normal and malignant hematopoiesis in immunodeficient mice [PDF]
, 2018 There is still an unmet need for xenotransplantation models that efficiently recapitulate normal and malignant human hematopoiesis. Indeed, there are a number of strategies to generate humanized mice and specific protocols, including techniques to ...
A Rambaldi +17 more
core +1 more source
Congenital Athymia: Unmet Needs and Practical Guidance
Therapeutics and Clinical Risk Management, 2023 Evey Howley,1 E Graham Davies,1 Alexandra Y Kreins1,2 1Department of Immunology and Gene Therapy, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK; 2Infection, Immunity and Inflammation Research & Teaching Department, University
Howley E, Davies EG, Kreins AY
doaj
Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice. [PDF]
PLoS ONE, 2015 We have used homozygous albumin enhancer/promoter-driven urokinase-type plasminogen activator/severe combined immunodeficient (uPA/SCID) mice as hosts for chimeric mice with humanized livers.
Chise Tateno +17 more
doaj +1 more source
Diagnostic value of the Dutch version of the MCclean Screening instrument for BPD (MSI-BPD) [PDF]
, 2015 Borderline personality disorder (BPD) often goes unrecognized, and therefore a short but accurate screening tool is desired. The present study investigated the psychometric properties of the 10-item McLean Screening Instrument for BPD (MSI-BPD) in 159 ...
Andre, JA +2 more
core +2 more sources
Differentiation of Uterine Natural Killer Cells in Pregnant SCID (scid/scid) Mice
Journal of Veterinary Medical Science, 2011 To determine whether functional T- and B-cells can affect differentiation and/or proliferation of uterine natural killer (uNK) cells, their numbers in SCID mice (genotype, C.B.-17/Icr-scid/scid) were compared with those of control mice (genotype, C.B.-17/Icr-+/+) on days 8, 12 and 16 of pregnancy.
Masato, Hiyama +5 more
openaire +3 more sources
Disease Models & Mechanisms, 2019 Mutations in the gene AK2 are responsible for reticular dysgenesis (RD), a rare and severe form of primary immunodeficiency in children. RD patients have a severely shortened life expectancy and without treatment die, generally from sepsis soon after ...
Alberto Rissone +8 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2020 Background & Aims: Organ-level research using an animal model lacking Il2rg, the gene responsible for X-linked severe combined immunodeficiency (X-SCID), is clinically unavailable and would be a powerful tool to gain deeper insights into the symptoms
Tomonori Nochi +19 more
doaj +1 more source