Results 211 to 220 of about 192,238 (309)

A patient‐derived orthotopic xenograft model unveils metastatic dynamics in head and neck squamous cell carcinoma

open access: yesThe FEBS Journal, EarlyView.
Metastasis in head and neck squamous cell carcinoma (HNSC) poses significant clinical challenges. This proof‐of‐concept study establishes patient‐derived orthotopic xenografts (PDOXs) as advanced models that closely replicate primary HNSC tumours, including local lymph node metastasis and the intricate cancer–stroma interaction.
Yuchen Bai   +5 more
wiley   +1 more source

A comparison of an anti‐gastrin antibody and cytotoxic drugs in the therapy of human gastric ascites in SCID mice [PDF]

open access: bronze, 1999
Sue‐Ann Watson   +8 more
openalex   +1 more source

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

open access: yesHistopathology, EarlyView.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai   +6 more
wiley   +1 more source

Human Gut Commensal Bacteroides fragilis Suppresses Mucin Production and Alters Microbiota Composition Resulting in Accelerated Type 1 Diabetes in Mice

open access: yesImmunology, EarlyView.
We show that gut colonisation of specific pathogen‐free (SPF) and germ‐free (GF) non‐obese diabetic (NOD) mice by Bacteroides fragilis (BF) at a juvenile age induces a pro‐inflammatory immune response and accelerated type 1 diabetes progression. Gut microbiota composition was different in control and BF‐colonised SPF mice, and the presence of BF alone ...
Radhika R. Gudi   +7 more
wiley   +1 more source

General Dementia Training for the Social Care Workforce: A Systematic Review

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim The aim of this systematic review was to assess and synthesize the global evidence on existing general dementia training and education for the social care workforce. Design Mixed‐methods systematic review. Data Sources Systematic searches on five databases (PubMed, APA PsychINFO, CINAHL Plus, Scopus, Web of Science) were conducted for ...
Clarissa Giebel   +10 more
wiley   +1 more source

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