Results 191 to 200 of about 187,417 (303)

Derivation of an updated brief multivariable prediction model to detect panic-related anxiety in emergency department patients with cardiopulmonary complaints. [PDF]

Front Psychiatry
Sung SC, Ang FJL, Earnest A, Lim LEC, Jolly S, Ng G, Rush AJ, Ong MEH.   +7 more
europepmc   +1 more source

Clinical Factors Influencing Improvement in Disorganization in Clinical High‐Risk for Psychosis: Preliminary Findings From a 2‐Year Follow‐Up

Asia-Pacific Psychiatry, Volume 18, Issue 2, June 2026.
ABSTRACT Disorganization is under‐treated in early psychosis. We aimed at exploring clinical factors potentially improving disorganization in individuals at Clinical High Risk for Psychosis (CHR‐P) across 2 years of follow‐up. About 180 participants completed the GAF and the PANSS.
Lorenzo Pelizza, Emanuela Leuci, Emanuela Quattrone, Michele Occhionero, Arianna Biancalani, Derna Palmisano, Simona Pupo, Giuseppina Paulillo, Clara Pellegrini, Pietro Pellegrini, Marco Menchetti   +10 more
wiley   +1 more source

Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives

British Journal of Pharmacology, Volume 183, Issue 11, Page 3015-3031, June 2026.
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano, Mikako Nishida, Miho Tokumasu, Weiyang Zhao, Nahoko Yamashita, Heiichiro Udono   +5 more
wiley   +1 more source

BCG vaccination in Korea, Japan, and Taiwan: Current status and future perspectives. [PDF]

Hum Vaccin Immunother
Choe YJ, Kim KJ, Yoshida LM, Toizumi M, Lin YC.   +4 more
europepmc   +1 more source

Synergistic Effects of DNA‐PKcs Inhibition and Radiotherapy in Esophageal Squamous Cell Carcinoma

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Radiotherapy induces double‐strand DNA breaks in esophageal squamous cell carcinoma, triggering DNA‐PKcs phosphorylation and activating the non‐homologous end joining (NHEJ) repair pathway, which contributes to radioresistance. Inhibiting DNA‐PKcs disrupts this repair mechanism, enhancing radiosensitivity by blocking NHEJ, amplifying DNA damage, and ...
Jiekun Qian, Guoliang Liao, Jianting Du, Maojie Pan, Maohui Chen, Long Wu, Xin Yan, Chun Chen, Bin Zheng, Zhang Yang   +9 more
wiley   +1 more source

Implementation Timeframes for the Addition of New Conditions to Newborn Bloodspot Screening Programmes: A Scoping Review. [PDF]

Int J Neonatal Screen
Brennan MM, O'Connell A, O'Grady L, Elsammak M, Brady JJ, Marsden P, Burns H, Collins A.   +7 more
europepmc   +1 more source

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]

, 2018
Denner, Joachim, Schuurman, Henk-Jan, Scobie, Linda   +2 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, Volume 20, Issue 5, Page 1347-1363, May 2026.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, Volume 20, Issue 5, Page 1115-1139, May 2026.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The interrater reliability of the Swedish version of the Structured Clinical Interview for the DSM-5 Alternative Model for Personality Disorders, Module I and Module II for diagnosing personality disorders among adults referred to specialized psychiatric care - a pilot study. [PDF]

BMC Psychiatry
Steijer S, Steingrimsson S, Meyerson N, Sand P.   +3 more
europepmc   +1 more source