<i>Borrelia mayonii</i> induces carditis but not arthritis in Lyme-susceptible mice. [PDF]
Cleveland DW +5 more
europepmc +1 more source
ABSTRACT Cluster‐C personality disorders (PDs) are common in the general population but often overlooked in scientific research and clinical practice. An important step to increase awareness for timely diagnosis and treatment of cluster‐C PDs is to investigate the burden of disease in terms of quality of life (QoL), daily functioning and the associated
Iuno Z. Groot +5 more
wiley +1 more source
Lipopolysaccharide suppresses lung metastasis by activating CD8<sup>+</sup> T cells despite promoting effect via cancer-associated fibroblasts. [PDF]
Cui W +6 more
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
Lymphedema in patients with X-linked severe combined immunodeficiency. [PDF]
Consonni F +7 more
europepmc +1 more source
Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta +5 more
wiley +1 more source
RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids. [PDF]
Meng X +13 more
europepmc +1 more source
ABSTRACT Aims Characterising the association between childhood maltreatment (CM) and cognitive functioning in bipolar disorder (BD) is crucial for improving the understanding of how early environmental risk factors impact the presentation of the disorder.
Natalia E. Fares‐Otero +7 more
wiley +1 more source
Neurodevelopmental outcomes following hematopoietic cell transplantation for patients with severe combined immunodeficiency (SCID): A PIDTC study. [PDF]
Brumm VL +36 more
europepmc +1 more source
ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz +8 more
wiley +1 more source

