Results 91 to 100 of about 14,512,132 (358)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Math and Science Education Focus Groups: Summary [PDF]
, 2005 Summarizes the causes of low achievement in math and science and strategies for raising student interest, enhancing teacher quality and professional development, and improving curricula and teaching strategies, as discussed at a November 2004 ...
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Education SciencesWhile our world consistently presents complicated, interdisciplinary problems with STEM foundations, most pre-university curricula do not encourage drawing on multidisciplinary knowledge in the sciences and engineering to create solutions.
Nancy B. Songer +3 more
doaj +1 more source
Analogical Modelling in Science Education
Investigações em Ensino de Ciências, 2018 In this paper, we aimed at investigating: (i) the steps that can be used to guide the elaboration and the conduction of analogical modelling activities in science education; and (ii) the way in which the analogical modelling activities based on those ...
Nilmara Braga Mozzer +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
SCIENCE EFFICIENCY IN HIGHER EDUCATION
Вестник Северо-Кавказского федерального университета, 2022 For the first time, the article proposes a method for assessing the scientific effectiveness of state institutions of higher education "Science-Efficiency".
D. Segal
doaj
Can the science of Prosocial be a part of evolution education?
, 2020 We provide a brief overview of Prosocial: Using Evolutionary Science to Build Productive, Equitable, and Collaborative Groups by Paul Atkins, David Sloan Wilson, and Steven Hayes.
Eirdosh, D., Hanisch, S.
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Learning science and technology through cooperative education. [PDF]
, 2007 Cooperative education, a form of experiential or work‐integrated learning is common in tertiary educational institutions worldwide. However, in New Zealand few institutions provide work‐integrated learning programs in science or technology, and the ...
Coll, Richard K., Eames, Chris W.
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