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Journal of Interdisciplinary Sciences, 2017 Dear Readers, The Journal of Interdisciplinary Sciences (JIS) wishes to announce the publication of its first issue in November 2017 bringing together an assessment of the articles from the interdisciplinary sciences.
Mani Man Singh Rajbhandari
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What Makes Scientific Workflows Scientific? [PDF]
, 2009 A scientific workflow is the description of a process for accomplishing a scientific objective, usually expressed in terms of tasks and their dependencies [5]. While workflows have a long history in the database community as well as in business process modeling (where they are also known as business workflows ), and despite some early works on ...
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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ISLAM : ILMIAH DAN DAKWAH (Perspektif Filsafat Ilmu)
Jurnal Ilmu Agama: Mengkaji Doktrin, Pemikiran, dan Fenomena Agama, 2016 This study sought to reinforce differences, as well as to find forms or teleological principles between scientific of Islam and Islamic preaching mission. The research use integrative, descriptive and analytical approaches on the existing bibliographical
Syefriyeni Syefriyeni
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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STAR Guideline Terminology (I): Planning and Launching
Xiehe Yixue ZazhiObjectiveTo develop a guideline terminology system and promote its standardization, thereby enhancing medical staff's accurate understanding and correct application of guidelines.MethodsA systematic search was conducted for guideline development manuals ...
LI Zhewei +8 more
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Scientific Misconduct, Kuhnian Scientific Revolutions and Scientific Ethics. [PDF]
, 2019 With increased occurrences of Scientific Misconduct in the form of Scientific Misconduct, Scientific Fraud and Dishonest Scientific Report being reported in leading Scientific Journals and in the regular press, it is befitting to ask whether Kuhns Theory of Scientific Revolutions foresaw the epidemic that afflicts the Scientific World and Enterprise ...
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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