Results 61 to 70 of about 4,109,881 (267)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Scientific misconduct and correcting the scientific literature
Academic Medicine, 1999 Journal editors are among those who must face the issue of when and how to correct the scientific literature when an allegation or finding of scientific misconduct occurs. The author describes an instructive incident of tainted data and a subsequent allegation of misconduct that involved a federally-sponsored study where some data had been fabricated ...
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Acknowledgement to reviewers [PDF]
Journal of Interdisciplinary Sciences, 2020 The Journal of Interdisciplinary Sciences (JIS) wishes to thank all the reviewers for their intellectual contributions by timely reviewing manuscripts, and supporting the journal’s vision of “Enriching Beautiful Minds towards Intelligent Minds”.
Editor-in-Chief
doaj
The Role of Scientific Collections in Scientific Preparedness
Emerging Infectious Diseases, 2015 Building on the findings and recommendations of the Interagency Working Group on Scientific Collections, Scientific Collections International (SciColl) aims to improve the rapid access to science collections across disciplines within the federal government and globally, between government agencies and private research institutions.
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Miniaturized Dual Band Implantable Antenna for Implanted Biomedical Devices
IEEE AccessIn this paper, we present a novel design of a compact miniaturized dual-band antenna for industrial, scientific, and medical (ISM) implantable applications working at 915 MHz and 2.4 GHz. The proposed antenna has a compact size of ( $6\times 6\times0.25$
Abdenasser Lamkaddem +3 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FORMS OF DISCURSIVE ENTITY IN THE WORK OF EMPLOYEES OF PROVINCIAL SCIENTIFIC ARCHIVAL COMMISSIONS
Гуманитарные и юридические исследования, 2021 This article considers the activity of provincial scientists of archival commissions, which originated in the late XIX - early XX centuries, as a complex, multi-layer, multi-level system.
A. Minina
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source