Results 111 to 120 of about 3,852,365 (305)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Theorica et Practica: Historical Epistemology and the Re-Visioning of Thirteenth and Fourteenth-Century Medicine [PDF]

, 2011
Positivist medical historians, guided by the savoir of modern western biomedicine, have long depicted medieval medicine as an aberration along the continuum of scientific and medical progress.
Gardenour, Brenda S.
core  

Beyond high hopes: A scoping review of the 2019-2021 scientific discourse on machine learning in medical imaging. [PDF]

PLOS Digit Health, 2023
Nittas V, Daniore P, Landers C, Gille F, Amann J, Hubbs S, Puhan MA, Vayena E, Blasimme A.   +8 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Science, Politics, and Values: The Politicization of Professional Practice Guidelines [PDF]

, 2009
The Connecticut Attorney General’s recent allegations that the Infectious Disease Society of America violated antitrust law through its treatment guidelines for Lyme disease were neither based in sound science or appropriate legal judgment.
Gostin, Lawrence O., Kraemer, John D.
core   +1 more source

La lecture académique dans la perspective d’un écrit de transition

Studia Romanica Posnaniensia
Academic reading can have different epistemic objectives and be situated at different levels, such as the development of disciplinary knowledge, the observation and development of scientific reasoning, as well as the awareness and refinement of reading ...
Bernadeta Wojciechowska, Katarzyna Karpińska-Szaj   +1 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Scientific innovation and its representation in discourse [PDF]

, 2017
The article is devoted to the representation problem of innovation as a linguistic-cultural concept of objectification "new" in the scientific-innovative discourse representing a communication tool with a complex macrostructure of language units ...
Evdokimova, Nadejda Veniaminovna, Evsukova, Tatyana Vsevolodovna, Germasheva, Tatyana Martirosovna, Kotelnikova, Evgenya Vladimirovna   +3 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A Map of the Nanoworld: Sizing up the Science, Politics, and Business of the Infinitesimal

, 2005
Mapping out the eight main nodes of nanotechnology discourse that have emerged in the past decade, we explore how various scientific, social, and ethical islands of discussion have developed, been recognized, and are being continually renegotiated. We do
Akhlesh Lakhtakia, Altmann, Arnall, Bagchi, Bainbridge, Bartlett, Baudrillard, Bendle, Bidwai, Braun, Brumfiel, Cobb, Crichton, Davies, Debashish Munshi, Dewick, DiLoreto, Drexler, Drexler, Drexler, Dunkley, Elliott, Eto, Feynman, Fiedler, Fischer, Friedman, Fukuyama, Gaskell, Gilman, Gimzewski, Gogotsi, Hajer, Halluin, Harding, Highfield, Hoet, Horn, Hullmann, Jones, Kapoor, Kay, Kerr, Kostoff, Kurzweil, Lakhtakia, Lewenstein, Lin-Easton, Malakoff, Marlowe, McKibben, Meyer, Milburn, Mnyusiwalla, Montague, Mulhall, Murday, Newberger, Otway, Phoenix, Picariello, Poole, Priya Kurian, Ravetz, Reynolds, Robert V. Bartlett, Robichaud, Roco, Rosenberg, Satava, Schummer, Service, Shindo, Smith, Stephenson, Steyn, Thomas, Thomas, Thomas, Thomas, Thompson, Tolles, Weil, Winner   +83 more
core   +2 more sources