Results 121 to 130 of about 22,383,729 (330)

Detecting Elemental Impurities by Inductively Coupled Plasma Mass Spectrometry in Russian Radiopharmaceuticals

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Radiopharmaceutical manufacturers should assess potential negative impact of elemental impurities on the quality of their products using real data of their elemental contamination.
Yu. N. Shvetsova, A. A. Erina, V. M. Shchukin, N. E. Kuz'mina, R. D. Ruziev, D. A. Pripadchev, M. A. Kuznetsov   +6 more
doaj   +1 more source

Integrating scientific assessment of wetland areas and economic evaluation tools to develop an evaluation framework to advise wetland management [PDF]

Wetland ecosystems provide society with a range of valuable ecosystem services. However, wetlands worldwide are experiencing increasing pressure from a number of sources, caused by an interrelated combination of market failure and policy intervention ...
Gabriella Schaffer, Jackie Robinson, Jared Dent   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article describes validation of the procedure for determination of amino acids composition of glatiramer acetate by C-13 NMR spectroscopy. The procedure makes it possible to determine the molar ratio of amino acids present in glatiramer acetate with ...
N. E. Kuz’Mina, S. V. Moiseev, V. I. Krylov, A. A. Kutin, E. A. Zhukov, V. A. Yashkir, V. A. Merkulov   +6 more
doaj  

Generating Multi-Functional Pulse Ingredients for Processed Meat Products-Scientific Evaluation of Infrared-Treated Lentils. [PDF]

Foods, 2023
Pathiraje D, Carlin J, Der T, Wanasundara JPD, Shand PJ.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Results of an opinion poll devoted to unification of instructions for interchangeable medicines

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article discusses the results of an opinion poll among healthcare professionals and pharmacists devoted to finding out their attitude to the main problems associated with instructions for medicinal products. It was discovered that there was a lack of
N. G. Goloenko, R. I. Yagudina, B. K. Romanov, D. G. Karapetyan, A. Yu. Kulikov, M. V. Protsenko, G. T. Abdrashitova   +6 more
doaj  

Scientific evaluation of alleged findings in HPV vaccines: Molecular mimicry and mouse models of vaccine-induced disease. [PDF]

Cancer Sci, 2022
Matsumura N, Tsunoda I.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Requirements for the information on reference standards submitted in the dossier for biologicals

Биопрепараты: Профилактика, диагностика, лечение
SCIENTIFIC RELEVANCE. The use of appropriately certified reference standards (RSs) is a necessary element of analytical procedure standardisation that ensures comparability of results across different laboratories assessing the quality of medicines ...
R. A. Volkova, O. V. Fadeikina, O. B. Ustinnikova, K. A. Sarkisyan, A. A. Movsesyants, V. A. Merkulov, V. V. Kosenko   +6 more
doaj   +1 more source