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Are current etiological theories of Alzheimer’s disease falsifiable? An epistemological assessment [PDF]

Frontiers in Aging Neuroscience
Alzheimer’s disease (AD) research is plagued by a proliferation of competing etiological theories, often coexisting without undergoing systematic critical comparison. This article examines the epistemological limitations of the traditional falsifiability
Tommaso Costa, Tommaso Costa, Tommaso Costa, Donato Liloia, Donato Liloia   +4 more
doaj   +2 more sources

Scenarios of land use and land cover change in the Colombian Amazon to evaluate alternative post-conflict pathways

Scientific Reports, 2023
Pastures and crops have been expanding at an accelerated rate in the forests of the Colombian Amazon since the peace accords were signed in 2016. The rapid loss of tropical rainforests is threatening the integrity of protected areas and connectivity in ...
William-J. Agudelo-Hz, Natalia-C. Castillo-Barrera, Murcia-García Uriel   +2 more
doaj   +1 more source

Concordism and the Importance of Hybrid Models

Religions, 2023
Concordism functioned as the consensus view in Protestant circles until the rise of Darwinism. Darwinism upended evangelical beliefs about the relationship between the Bible and science, and concordism began to fall out of favor.
Theodore James Cabal
doaj   +1 more source

Inference to the best action and its basis in clinical expertise

Frontiers in Psychology, 2023
Can contemporary cognitive science explain clinical expertise? We argue that the answer could be “no.” In support of this, we provide an analysis of two of the most essential expressions of clinical expertise in nursing and medicine, the ability to run a
Mark Fedyk, Mark Fedyk, Jessica Draughon Moret, Nicolas T. Sawyer   +3 more
doaj   +1 more source

The age of our universe [PDF]

Hemijska Industrija, 2008
If we assume that the observed Redshift of starlight is due to the Doppler effect we end up with models of the universe which contradict the basic laws of science. If we assume that the red shift may be due to a tiring of light, an assumption still to be
Levenspiel Octave
doaj   +1 more source

In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination

npj Vaccines, 2021
Novel tuberculosis (TB)-vaccines preferably should (i) boost host immune responses induced by previous BCG vaccination and (ii) be directed against Mycobacterium tuberculosis (Mtb) proteins expressed throughout the Mtb infection-cycle.
Mariateresa Coppola, Fabienne Jurion, Susan J. F. van den Eeden, Hermann Giresse Tima, Kees L. M. C. Franken, Annemieke Geluk, Marta Romano, Tom H. M. Ottenhoff   +7 more
doaj   +1 more source

Different Roles for Multiple Perspectives and Rigorous Testing in Scientific Theories and Models: Towards More Open, Context-Appropriate Verificationism

Philosophies, 2022
A form of context-appropriate verificationism is proposed that distinguishes between scientific theories as evolving systems of ideas and operationally-specified, testable formal-empirical models.
Peter Cariani
doaj   +1 more source

The Development of Attitudes Toward Scientific Models During a Participatory Modeling Process – The Impact of Participation and Social Network Structure

Frontiers in Marine Science, 2020
Scientific models are increasingly being used to support participatory natural resources management decision making processes. These models allow stakeholders and scientists to explore potential policy and management options and can help facilitate ...
Taylor Goelz, Taylor Goelz, Troy Hartley, Troy Hartley, Andrew Scheld, Inga Carboni   +5 more
doaj   +1 more source

CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors

Signal Transduction and Targeted Therapy, 2023
As the most prevalent neurodevelopmental disorders in children, autism spectrum disorders (ASD) are characterized by deficits in language development, social interaction, and repetitive behaviors or inflexible interests. Contactin associated protein like
Jing Zhang, Fang Cai, Renbin Lu, Xiaoliang Xing, Lu Xu, Kunyang Wu, Zishan Gong, Qing Zhang, Yun Zhang, Mengen Xing, Weihong Song, Jia-Da Li   +11 more
doaj   +1 more source

Models, Brains, and Scientific Realism [PDF]

, 2006
Prediction Error Minimization theory (PEM) is one of the most promising attempts to model perception in current science of mind, and it has recently been advocated by some prominent philosophers as Andy Clark and Jakob Hohwy. Briefly, PEM maintains that “
Sterpetti, Fabio
core   +1 more source