Results 81 to 90 of about 11,703,274 (378)

Memoir of the III simposio latinoamericano de briologia : briología en el beotrópico July 13-17, 1992 - Mexico City, Mexico [PDF]

, 1992
Botanical history has recorded significant contributions of bryology to its conceptual development and to man’s scientific knowledge. The discovery of sexual chromosomes in plants by Allen and the production of the first polyploids by Wettstein are but ...

core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Comparative research of bounding box based and image segmentation based neural network models for individual cattle identification [PDF]

E3S Web of Conferences
Software and hardware based tools for collecting information about animals are an important part of most large agricultural enterprises. Various information collection methods and technologies help farmers to receive data about the health, behavior and ...
Shilin Denis, Shubin Ivan, Shestov Dmitry   +2 more
doaj   +1 more source

A plant-biotechnology approach for producing highly potent anti-HIV antibodies for antiretroviral therapy consideration

Journal of Genetic Engineering and Biotechnology, 2021
Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority.
Advaita Acarya Singh, Priyen Pillay, Lusisizwe Kwezi, Tsepo Lebiletsa Tsekoa   +3 more
doaj   +1 more source

PROXIMITY OF FIRMS TO SCIENTIFIC PRODUCTION

Annals of Economics and Statistics
Following Bergeaud et al. (2022), we construct a new measure of proximity between industrial sectors and public research laboratories. Using this measure, we explore the underlying network of knowledge linkages between scientific fields and industrial sectors in France.
Bergeaud, Antonin, Guillouzouic, Arthur
openaire   +3 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

RESULTS OF A MULTICENTER CLINICAL STUDY OF A NEW COMBINATION VACCINE DTaP-HepB+Hib PRODUCTION OF THE CPA «MICROGEN» FOR IMMUNIZATION OF CHILDREN 6 MONTHS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. The aim of the study is evaluate of reactogenicity, safety and immunogenicity of the native combined vaccine DTaP-HepB+Hib. Materials and methods. Assessment of reactogenicity, safety and immunogenicity of the drug is investigated in a multicenter ...
I. V. Feldblyum, V. V. Romanenko, A. M. Nikolaeva, K. A. Subbotina, O. Yu. Sosnina, O. A. Perminova, O. V. Belyakova, T. V. Danilina, A. E. Ershov, D. M. Trofimov, E. A. Bykova, S. V. Martirosyan, A. V. Ankudinova   +12 more
doaj   +1 more source

The graying of academia: Will it reduce scientific productivity? [PDF]

American Psychologist, 2010
The belief that science is a young person's game and that only young scientists can be productive and publish high-quality research is still widely shared by university administrators and members of the scientific community. Since the average age of university faculties is increasing not only in the United States but also in Europe, the question arises
openaire   +5 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source