Results 81 to 90 of about 2,685,069 (299)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

El naturalismo científico de Ronald Giere y Philip Kitcher.

open access: yesRevista de Filosofia, 2000
Se discute el proyecto de la naturalización de la filosofía de la ciencia, a través de las teorías de Ronald Giere y Philip Kitcher. Ambas tienen en común la atención preferente que prestan a los procesos de decisión de los científicos individuales y ...
Jesús Zamora Bonilla
doaj  

ANÁLISIS DEL TIPO DE INTERACCIONES QUE OCURREN ENTRE INVESTIGADORES DURANTE LA PRESENTACIÓN DE TRABAJOS ACADÉMICOS

open access: yesActa Colombiana de Psicología, 2014
Although it is considered that scientific development and intellectual progress occur through the exchange of ideas brought about by the interaction among scientists, the type of interactions that take place among researchers when one of them presents ...
Padilla Vargas, María Antonia
doaj   +1 more source

MODELING OF SCIENTIFIC AND TECHNICAL PROGRESS

open access: yesСтатистика и экономика, 2016
Scientific and technical progress can be represented in the form of an active medium in which they are earned achievements of the company. For modeling scientific and technological progress used standard mathematical models of self-organization, is ...
Michael E. Mazurov
doaj   +1 more source

Coming together to document mortality in conflict situations : proceedings of a symposium [PDF]

open access: yes, 2009
The use of epidemiology in documenting the mortality experience in complex emergencies has become pervasive in humanitarian practice. Recent assessments in Iraq and Darfur have provoked much discussion on the assessment of mortality in scientific and ...
Degomme, Olivier   +2 more
core   +4 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TECHNICAL SCIENTIFIC PROGRESS AND SOCIETY DEVELOPMENT [PDF]

open access: yesFiabilitate şi Durabilitate, 2020
This paper conducts a study on the role of science in technical and scientific progress and development of society, for a technological economy and in the evolution of modern technological society, information society (digitization, digital signal ...
Adina TĂTAR
doaj  

The Ascent of Man? Emil du Bois-Reymond's Reflections on Scientific Progress [PDF]

open access: yes, 2000
Triumphalist histories of science are nothing new but were, in fact, a staple of the 19th century. This article considers one of the more famous works in the genre and argues that it was motivated by doubt more than by ...
Finkelstein, Gabriel
core  

On Phenomenology of Complex Scientific Systems

open access: yes, 2011
Performance evolution of a number of complex scientific and technical systems demonstrate exponential progress with time exp(+t/C) . The speed of progress C - a measure of difficulty and complexity - is analyzed for high energy elementary particle ...
Shiltsev, Vladimir
core   +1 more source

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