Results 61 to 70 of about 12,648 (296)
The realist claim of fallibilism: A critique of the realism of Karl Popper
Pensamiento. Revista de Investigación e Información Filosófica, 2015 This article revises Karl Popper’s realism and examines how far he was a realist or simply he tried to be. Distinguishing between two areas of realism, a general one against the idealism, and the other more specific as part of the philosophy of the ...
Rafael Fayos Febrer
doaj
American Legal Realism: Research Programme and Policy Impact
Utrecht Law Review, 2017 The article addresses two questions:1. Can Legal Realism be seen as a scientific research programme enabling growth of knowledge? To answer that question, the author uses Lakatos’s work on the methodology of scientific research programmes as a frame of ...
Frans L. Leeuw
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Realismo Científico Empirista?
Principia: An International Journal of Epistemology, 1997 In his influential criticism of scientific realism, Bas van Fraassen assumes that this doctrine is incompatible with empiricism, according to which the sole ultimate basis of knowledge is experience.
Sílvio Seno Chibeni
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Reasons versus causes in Arocha’s scientific realism
, 2021 Giuseppe Lo Dico
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Philosophia Scientiæ, 2015 “Naturalised realism” is presented as a version of realism which is more compatible with the history of science than convergent or explanationist forms of realism.
Emma Ruttkamp-Bloem
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
What Elements of Successful Scientific Theories Are the Correct Targets for “Selective” Scientific Realism? [PDF]
, 2014 Dean Peters
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