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A study of the measurement characteristics of Lawson's test and its relationship to socio-demographic variables and physics grades [PDF]
The aim of the study presented in this paper was to test the measurement characteristics of Lawson's test of Scientific Reasoning (LTSR) and to examine the relationship between scientific reasoning levels on the one hand, and socio-demographic variables ...
Radulović Branka N. +1 more
doaj
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
In an era of pervasive misinformation, understanding the cognitive factors that reduce susceptibility to conspiracy theories is of growing societal and scientific importance.
Peter Teličák +3 more
doaj +1 more source
While previous research has shown that claim-evidence-reasoning can effectively promote higher-order thinking skills in science education, more research should be done on using claim-evidence-reasoning in elementary school settings. This study aims to investigate the effectiveness of claim-evidence-reasoning in promoting the scientific reasoning skills
Winona Y. Diola +2 more
openaire +1 more source
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Measurement Model of Reasoning Skills among Science Students Based on Socio Scientific Issues (SSI)
The lack of reasoning skills has been recognized as one of the contributing factors to the declined achievement in the Trends in Mathematics and Science Studies (TIMSS) and Programme for International Student Assessment (PISA) assessments in Malaysia ...
MOHD AFIFI BAHURUDIN SETAMBAH
doaj
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source

