Results 121 to 130 of about 22,645,468 (334)
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Tensions et coordinations entre les acteurs des sciences de la performance sportive
This article is based on a study which examines how knowledge is produced in the field of sports performance, looking at the modes of coordination between researchers and the coaches with whom they collaborate.
Matthieu Delalandre
doaj
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
SciPub–019–Getting Your Article Published in Scientific Journals- an Event Report
Nisha Jha, 1 Ranish Shrestha, 2 Sunil Shrestha, 3 Shital Bhandary, 4 Anil Khadka, 5 Pathyil Ravi Shankar 6 1Department of Pharmacology, KIST Medical College, Gwarko, Lalitpur, Nepal; 2Infection Control Unit, Nepal Cancer Hospital and Research Center ...
Jha N +5 more
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Active scientific research management model and optimization decision mechanism based on big data
During the scientific research management,a large number of data could be accessed from researchers,projects,output and other multi-dimensional.The big data of scientific research management implicitly contains tremendous highlyinterconnected knowledge ...
Ruili LUO, Yuanzhuo WANG
doaj
The critical steps for successful research: The research proposal and scientific writing
Pitchai Balakumar +2 more
openalex +2 more sources
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source

