Results 111 to 120 of about 57,119,191 (293)

SciPub–019–Getting Your Article Published in Scientific Journals- an Event Report

open access: yesJournal of Multidisciplinary Healthcare, 2020
Nisha Jha, 1 Ranish Shrestha, 2 Sunil Shrestha, 3 Shital Bhandary, 4 Anil Khadka, 5 Pathyil Ravi Shankar 6 1Department of Pharmacology, KIST Medical College, Gwarko, Lalitpur, Nepal; 2Infection Control Unit, Nepal Cancer Hospital and Research Center ...
Jha N   +5 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Directions for Developing the Efficiency of Scientific Research

open access: yesRevista Română de Biblioteconomie și Știința Informării, 2019
The article surprises elements of novelty and needs in the activity of scientific research and communication, identifies the needs and their practical settlement.
Ionela Maria Bârsan
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

African Small Mammals (Macroscelidea and Rodentia) Housed at the National Museum of Natural History and Science (University of Lisbon, Portugal)

open access: yesDiversity
The National Museum of Natural History and Science holds a historical collection of 279 small African mammal specimens (Macroscelidea and Rodentia), representing 32 species, gathered during the Portuguese colonial period in Mozambique, Angola, and Guinea-
Maria da Luz Mathias, Rita I. Monarca
doaj   +1 more source

Phenocam - Green Chromatic Coordinates (GCC) Composite Image Mean Values from Abisko Scientific Research Station, Mast 4.5m Phenocam 01

open access: yes, 2022
Green Chromatic Index (GCI) also known as Green Chromatic Coordinate (GCC) is a measure of the greenness of vegetation.  It is calculated from daily averaged RGB (Red, Green, Blue) composites values of digital images captured by PhenoCams.
Abisko Scientific Research Station
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Phenocam - Green Chromatic Coordinates (GCC) Composite Image Mean Values from Abisko Scientific Research Station

open access: yes
Green Chromatic Index (GCI) also known as Green Chromatic Coordinate (GCC) is a measure of the greenness of vegetation.  It is calculated from daily averaged RGB (Red, Green, Blue) composites values of digital images captured by PhenoCams.
Abisko Scientific Research Station
core   +2 more sources

Home - About - Disclaimer - Privacy