Results 91 to 100 of about 9,382,254 (295)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Does poverty research in Russia follow the scientific method? [PDF]
This paper presents the first critical review of literature on poverty published in Russia between 1992 and 2006. Using a dataset of about 250 publications in Russian scientific journals, the authors assess whether the poverty research in Russia ...
Lokshin, Michael
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
"Three pillars" of science: scientific knowledge - scientific research - scientific knowledge [PDF]
, 2016 Підготовка дисертаційного дослідження – важливий етап у науковому зростанні молодого вченого. Для того щоб він був успішним і дисертант отримав результати, які стануть реальним внеском у розвиток наукового знання, необхідно, щоб він чітко усвідомлював зв’
Отич, О.М.
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The Child is Father of the Man: Foresee the Success at the Early Stage
, 2015 Understanding the dynamic mechanisms that drive the high-impact scientific work (e.g., research papers, patents) is a long-debated research topic and has many important implications, ranging from personal career development and recruitment search, to the
Golub G. H. +3 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
More in Defense of Weak Scientism [PDF]
, 2018 In my (2017a), I defend a view I call Weak Scientism, which is the view that knowledge produced by scientific disciplines is better than knowledge produced by non-scientific disciplines.
Mizrahi, Moti
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, 2016 In experimental physics, lab notebooks play an essential role in the research process. For all of the ubiquity of lab notebooks, little formal attention has been paid to addressing what is considered `best practice' for scientific documentation and how ...
Lewandowski, H. J., Stanley, Jacob T.
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Heterogeneity of Patenting Activity and Its Implications for Scientific Research [PDF]
The increasing commercialization of university discoveries has initiated a controversy on the impacts for future scientific research. It has been argued that an increasing orientation towards commercialization may have a negative impact on more ...
Czarnitzki, Dirk +2 more
core +3 more sources