Results 71 to 80 of about 9,382,254 (295)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Good scientific practice and ethical principles in scientific research and higher education
Central European Journal of Sport Sciences and Medicine, 2013 High ethical standards constitute the foundation of high-quality scientific research. Scientific research as a public trust must be conducted according to specific codes, rules, governmental laws, and regulations relating to research ethics.
Joanna Kruk
doaj
HPC Cloud for Scientific and Business Applications: Taxonomy, Vision, and Research Challenges
, 2018 High Performance Computing (HPC) clouds are becoming an alternative to on-premise clusters for executing scientific applications and business analytics services.
Buyya, Rajkumar +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Polémicas e Modelos para uma Sociologia de Intervenção
Cadernos de Estudos Africanos, 2003 The sociology of intervention has always defined its central challenge as the utopian search for the key to social change, and using this theoretical reflection, to test methods of reducing uncertainty. This has now produced a long history of theoretical,
Isabel Guerra
doaj +1 more source
Modeling and Analysis of Scholar Mobility on Scientific Landscape
, 2015 Scientific literature till date can be thought of as a partially revealed landscape, where scholars continue to unveil hidden knowledge by exploring novel research topics. How do scholars explore the scientific landscape , i.e., choose research topics to
Chiu, Dah Ming +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A Novel Rubric for Rating the Quality of Retraction Notices
Publications, 2014 When a scientific article is found to be either fraudulent or erroneous, one course of action available to both the authors and the publisher is to retract said article. Unfortunately, not all retraction notices properly inform the reader of the problems
Emma Bilbrey +2 more
doaj +1 more source
Industry funding of university research and scientific productivity. [PDF]
University research provides valuable inputs to industrial innovation. It is therefore not surprising that private sector firms increasingly seek direct access through funding public R&D.
Hottenrott, Hanna, Thorwarth, Susanne
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source