Results 61 to 70 of about 4,856,383 (280)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Economic and social studies of scientific research: nature and origins [PDF]
Interest in the role that science and scientific research play in economics and the other social sciences has exploded in the last fifty years. This attention undoubtedly reflects the increased importance that scientific research is contributing more and
Mario Coccia
core
Green Chromatic Index (GCI) also known as Green Chromatic Coordinate (GCC) is a measure of the greenness of vegetation. It is calculated from daily averaged RGB (Red, Green, Blue) composites values of digital images captured by PhenoCams.
Abisko Scientific Research Station
core +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
SCIENTOMETRY AND EVALUATION OF THE RESULTS OF ECONOMIC SCIENTIFIC RESEARCH [PDF]
Economica, 2017 Starting from the necessity of a continuous and demanding evaluation, capable of linking the results obtained with the human, material and financial resources, allocated and periodically setting the position of the national research relative to the ...
Ana-Lucia RISTEA +3 more
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
A plan for acupuncture-moxibustion scientific research
针刺研究The establishment of the “Acupuncture Scientific Research Alliance” aims to realize the collaborative innovation of scientific research， clinical transformation and equipment development through multidisciplinary cooperation.
Acupuncture Scientific Research Alliance
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Good scientific practice and ethical principles in scientific research and higher education
Central European Journal of Sport Sciences and Medicine, 2013 High ethical standards constitute the foundation of high-quality scientific research. Scientific research as a public trust must be conducted according to specific codes, rules, governmental laws, and regulations relating to research ethics.
Joanna Kruk
doaj